ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Immunophilins 14 coordinate concepts 2 subordinate concepts ∟ Cyclophilins \| ∟ Tacrolimus Binding Proteins ∟ Receptors, Phencyclidine \| ∟ Antigens, CD14 \| ∟ Integrins \| ∟ Platelet Membrane Glycoproteins \| ∟ Receptors, Antigen \| ∟ Receptors, Complement \| ∟ Receptors, Cytokine \| ∟ Receptors, Fc \| ∟ Receptors, Formyl Peptide \| ∟ Receptors, Laminin \| ∟ Receptors, Lymphocyte Homing \| ∟ Receptors, Mitogen \| ∟ Receptors, Pattern Recognition \| ∟ Receptors, Scavenger Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Receptors, Drug ∟ Immunophilins 14 coordinate concepts 2 subordinate concepts ∟ Cyclophilins \| ∟ Tacrolimus Binding Proteins ∟ Receptors, Phencyclidine \| ∟ Antigens, CD14 \| ∟ Integrins \| ∟ Platelet Membrane Glycoproteins \| ∟ Receptors, Antigen \| ∟ Receptors, Complement \| ∟ Receptors, Cytokine \| ∟ Receptors, Fc \| ∟ Receptors, Formyl Peptide \| ∟ Receptors, Laminin \| ∟ Receptors, Lymphocyte Homing \| ∟ Receptors, Mitogen \| ∟ Receptors, Pattern Recognition \| ∟ Receptors, Scavenger Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Isomerases ∟ cis-trans-Isomerases ∟ Peptidylprolyl Isomerase ∟ Immunophilins 14 coordinate concepts 2 subordinate concepts ∟ Cyclophilins \| ∟ Tacrolimus Binding Proteins ∟ Receptors, Phencyclidine \| ∟ Antigens, CD14 \| ∟ Integrins \| ∟ Platelet Membrane Glycoproteins \| ∟ Receptors, Antigen \| ∟ Receptors, Complement \| ∟ Receptors, Cytokine \| ∟ Receptors, Fc \| ∟ Receptors, Formyl Peptide \| ∟ Receptors, Laminin \| ∟ Receptors, Lymphocyte Homing \| ∟ Receptors, Mitogen \| ∟ Receptors, Pattern Recognition \| ∟ Receptors, Scavenger X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Immunophilins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Receptors, Drug ∟ Immunophilins Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Isomerases ∟ cis-trans-Isomerases ∟ Peptidylprolyl Isomerase ∟ Immunophilins Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Receptors, Drug > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Peptidylprolyl Isomerase > cis-trans-Isomerases > Isomerases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Narrower terms:	Cyclophilins \| Tacrolimus Binding Proteins X
Annotation:	don't confuse X ref NEUROPHILINS with NEUROPILINS X
History note:	Immunosuppressive Agents (1990-1998)X
historyNote*:	2004(1999); for NEUROPHILIN use VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1997-2003 X
publicMeSHNote*:	2004; NEUROPHILIN was indexed under LYMPHOKINES 1974-2003; ENDOTHELIAL GROWTH FACTORS 1991-2003 & INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2002 X
Scope note:	Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotomase activity, which is inhibited by the immunosuppressant drugs that bind to them. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1998-06-10X
dateEstablished*:	1999-01-01X
dateRevised*:	2003-07-09X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	ADPX
Type:	Concept X
Coordinate terms:	Receptors, Phencyclidine \| Antigens, CD14 \| Integrins \| Platelet Membrane Glycoproteins \| Receptors, Antigen \| Receptors, Complement \| Receptors, Cytokine \| Receptors, Fc \| Receptors, Formyl Peptide \| Receptors, Laminin \| Receptors, Lymphocyte Homing \| Receptors, Mitogen \| Receptors, Pattern Recognition \| Receptors, Scavenger X
URI:	X
Labels and equivalent concepts:	Immunofiliinit (fi) Immunofiliini (fi, replaced) Immunfiliner (sv) Neurophilin (en, replaced) X
Share:	X