ONKI3 | Medical Subject Headings


Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ eIF-2 Kinase 43 coordinate concepts ∟ Activin Receptors \| ∟ Bone Morphogenetic Protein Receptors \| ∟ Ca(2+)-Calmodulin Dependent Protein Kinase \| ∟ Casein Kinases \| ∟ Cyclic Nucleotide-Regulated Protein Kinases \| ∟ Cyclin-Dependent Kinases \| ∟ DNA-Activated Protein Kinase \| ∟ Glycogen Synthase Kinases \| ∟ I-kappa B Kinase \| ∟ Interleukin-1 Receptor-Associated Kinases \| ∟ MAP Kinase Kinase Kinases \| ∟ Mitogen-Activated Protein Kinase Kinases \| ∟ Mitogen-Activated Protein Kinases \| ∟ Oncogene Protein v-akt \| ∟ Phytochrome A \| ∟ Proline-Directed Protein Kinases \| ∟ Protein Kinase C \| ∟ Proto-Oncogene Proteins c-akt \| ∟ Proto-Oncogene Proteins c-bcr \| ∟ Proto-Oncogene Proteins c-pim-1 \| ∟ Receptor-Interacting Protein Serine-Threonine Kinases \| ∟ Rhodopsin Kinase \| ∟ Ribosomal Protein S6 Kinases \| ∟ Activating Transcription Factor 6 \| ∟ Adaptor Proteins, Signal Transducing \| ∟ Adenylate Cyclase \| ∟ Apoptosis Regulatory Proteins \| ∟ Cyclin-Dependent Kinase Inhibitor Proteins \| ∟ Cyclins \| ∟ Focal Adhesion Protein-Tyrosine Kinases \| ∟ GTP-Binding Protein Regulators \| ∟ Guanylate Cyclase \| ∟ Heterotrimeric GTP-Binding Proteins \| ∟ I-kappa B Proteins \| ∟ Intracellular Calcium-Sensing Proteins \| ∟ Janus Kinases \| ∟ Monomeric GTP-Binding Proteins \| ∟ Olfactory Marker Protein \| ∟ Phosphatidylethanolamine Binding Protein \| ∟ Phospholipase C gamma \| ∟ Proto-Oncogene Proteins c-fyn \| ∟ PTEN Phosphohydrolase \| ∟ SHP1 Protein Tyrosine Phosphatase Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ eIF-2 Kinase 43 coordinate concepts ∟ Activin Receptors \| ∟ Bone Morphogenetic Protein Receptors \| ∟ Ca(2+)-Calmodulin Dependent Protein Kinase \| ∟ Casein Kinases \| ∟ Cyclic Nucleotide-Regulated Protein Kinases \| ∟ Cyclin-Dependent Kinases \| ∟ DNA-Activated Protein Kinase \| ∟ Glycogen Synthase Kinases \| ∟ I-kappa B Kinase \| ∟ Interleukin-1 Receptor-Associated Kinases \| ∟ MAP Kinase Kinase Kinases \| ∟ Mitogen-Activated Protein Kinase Kinases \| ∟ Mitogen-Activated Protein Kinases \| ∟ Oncogene Protein v-akt \| ∟ Phytochrome A \| ∟ Proline-Directed Protein Kinases \| ∟ Protein Kinase C \| ∟ Proto-Oncogene Proteins c-akt \| ∟ Proto-Oncogene Proteins c-bcr \| ∟ Proto-Oncogene Proteins c-pim-1 \| ∟ Receptor-Interacting Protein Serine-Threonine Kinases \| ∟ Rhodopsin Kinase \| ∟ Ribosomal Protein S6 Kinases \| ∟ Activating Transcription Factor 6 \| ∟ Adaptor Proteins, Signal Transducing \| ∟ Adenylate Cyclase \| ∟ Apoptosis Regulatory Proteins \| ∟ Cyclin-Dependent Kinase Inhibitor Proteins \| ∟ Cyclins \| ∟ Focal Adhesion Protein-Tyrosine Kinases \| ∟ GTP-Binding Protein Regulators \| ∟ Guanylate Cyclase \| ∟ Heterotrimeric GTP-Binding Proteins \| ∟ I-kappa B Proteins \| ∟ Intracellular Calcium-Sensing Proteins \| ∟ Janus Kinases \| ∟ Monomeric GTP-Binding Proteins \| ∟ Olfactory Marker Protein \| ∟ Phosphatidylethanolamine Binding Protein \| ∟ Phospholipase C gamma \| ∟ Proto-Oncogene Proteins c-fyn \| ∟ PTEN Phosphohydrolase \| ∟ SHP1 Protein Tyrosine Phosphatase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Phosphotransferases ∟ Phosphotransferases (Alcohol Group Acceptor) ∟ Protein Kinases ∟ Protein-Serine-Threonine Kinases ∟ eIF-2 Kinase 43 coordinate concepts ∟ Activin Receptors \| ∟ Bone Morphogenetic Protein Receptors \| ∟ Ca(2+)-Calmodulin Dependent Protein Kinase \| ∟ Casein Kinases \| ∟ Cyclic Nucleotide-Regulated Protein Kinases \| ∟ Cyclin-Dependent Kinases \| ∟ DNA-Activated Protein Kinase \| ∟ Glycogen Synthase Kinases \| ∟ I-kappa B Kinase \| ∟ Interleukin-1 Receptor-Associated Kinases \| ∟ MAP Kinase Kinase Kinases \| ∟ Mitogen-Activated Protein Kinase Kinases \| ∟ Mitogen-Activated Protein Kinases \| ∟ Oncogene Protein v-akt \| ∟ Phytochrome A \| ∟ Proline-Directed Protein Kinases \| ∟ Protein Kinase C \| ∟ Proto-Oncogene Proteins c-akt \| ∟ Proto-Oncogene Proteins c-bcr \| ∟ Proto-Oncogene Proteins c-pim-1 \| ∟ Receptor-Interacting Protein Serine-Threonine Kinases \| ∟ Rhodopsin Kinase \| ∟ Ribosomal Protein S6 Kinases \| ∟ Activating Transcription Factor 6 \| ∟ Adaptor Proteins, Signal Transducing \| ∟ Adenylate Cyclase \| ∟ Apoptosis Regulatory Proteins \| ∟ Cyclin-Dependent Kinase Inhibitor Proteins \| ∟ Cyclins \| ∟ Focal Adhesion Protein-Tyrosine Kinases \| ∟ GTP-Binding Protein Regulators \| ∟ Guanylate Cyclase \| ∟ Heterotrimeric GTP-Binding Proteins \| ∟ I-kappa B Proteins \| ∟ Intracellular Calcium-Sensing Proteins \| ∟ Janus Kinases \| ∟ Monomeric GTP-Binding Proteins \| ∟ Olfactory Marker Protein \| ∟ Phosphatidylethanolamine Binding Protein \| ∟ Phospholipase C gamma \| ∟ Proto-Oncogene Proteins c-fyn \| ∟ PTEN Phosphohydrolase \| ∟ SHP1 Protein Tyrosine Phosphatase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ eIF-2 Kinase Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ eIF-2 Kinase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Phosphotransferases ∟ Phosphotransferases (Alcohol Group Acceptor) ∟ Protein Kinases ∟ Protein-Serine-Threonine Kinases ∟ eIF-2 Kinase Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Protein-Serine-Threonine Kinases > Protein Kinases > Phosphotransferases (Alcohol Group Acceptor) > Phosphotransferases > Transferases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
History note:	Protein Kinases (1980-1993) \| Protein-Serine-Threonine Kinases (1993-1997)X
historyNote*:	98; use EIF-2 KINASE (NM) 1980-97 X
publicMeSHNote*:	98; EIF-2 KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1993-97 & PROTEIN KINASES 1980-93 X
Scope note:	A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis. X
activeMeSHYear*:	2005 \| 2006 \| 2006A \| 2007X
dateCreated*:	1997-07-02X
dateEstablished*:	1998-01-01X
dateRevised*:	2005-07-08X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	KEVX
Type:	Concept X
Coordinate terms:	Activin Receptors \| Bone Morphogenetic Protein Receptors \| Ca(2+)-Calmodulin Dependent Protein Kinase \| Casein Kinases \| Cyclic Nucleotide-Regulated Protein Kinases \| Cyclin-Dependent Kinases \| DNA-Activated Protein Kinase \| Glycogen Synthase Kinases \| I-kappa B Kinase \| Interleukin-1 Receptor-Associated Kinases \| MAP Kinase Kinase Kinases \| Mitogen-Activated Protein Kinase Kinases \| Mitogen-Activated Protein Kinases \| Oncogene Protein v-akt \| Phytochrome A \| Proline-Directed Protein Kinases \| Protein Kinase C \| Proto-Oncogene Proteins c-akt \| Proto-Oncogene Proteins c-bcr \| Proto-Oncogene Proteins c-pim-1 \| Receptor-Interacting Protein Serine-Threonine Kinases \| Rhodopsin Kinase \| Ribosomal Protein S6 Kinases \| Activating Transcription Factor 6 \| Adaptor Proteins, Signal Transducing \| Adenylate Cyclase \| Apoptosis Regulatory Proteins \| Cyclin-Dependent Kinase Inhibitor Proteins \| Cyclins \| Focal Adhesion Protein-Tyrosine Kinases \| GTP-Binding Protein Regulators \| Guanylate Cyclase \| Heterotrimeric GTP-Binding Proteins \| I-kappa B Proteins \| Intracellular Calcium-Sensing Proteins \| Janus Kinases \| Monomeric GTP-Binding Proteins \| Olfactory Marker Protein \| Phosphatidylethanolamine Binding Protein \| Phospholipase C gamma \| Proto-Oncogene Proteins c-fyn \| PTEN Phosphohydrolase \| SHP1 Protein Tyrosine Phosphatase X
URI:	X
Labels and equivalent concepts:	EIF-2-kinaasi (fi) eIF-2-kinas (sv) p68 Kinase (en, replaced) p65 Kinase (en, replaced) Hemin-Controlled Translational Repressor (en, replaced) Hemin Controlled Repressor (en, replaced) P68 Protein Kinase (en, replaced) Protein Kinase PKR (en, replaced) TIK Kinase (en, replaced) Self-Phosphorylating Protein Kinase (en, replaced) RNA-Dependent Protein Kinase (en, replaced) Protein Kinase, RNA Activated (en, replaced) Heme-Regulated eIF-2alpha Kinase (en, replaced) Heme-Controlled Translational Repressor (en, replaced) DSRNA-Dep Protein Kinase (en, replaced) dsRNA-Activated Inhibitor (en, replaced) Double Stranded RNA-Dependent Kinase (dsl) (en, replaced) Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase (en, replaced) eIF-2alpha Kinase (en, replaced) eRF, eIF-2 Recycling Factor (en, replaced) Heme-Controlled Inhibitor (en, replaced) Heme Controlled Repressor (en, replaced) Eukaryotic Initiation Factor 2alpha Kinase (en, replaced) DAI Protein Kinase (en, replaced) X
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