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The way concept relations are shown:
Mice, Inbred MRL lpr
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Mice, Inbred MRL lpr 13 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Mice, Inbred MRL lpr 13 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Mice, Inbred MRL lpr 13 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
Annotation: | a strain predisposed to develop of systemic lupus erythematosus; MRL stands for "Murphy-Roths Lymphoma", lpr stands for "LymphoPRoliferative"; NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check MICE; in titles & translations use lpr (the letter l), not 1pr (the figure one)
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History note: | Mice (1981-1996)X |
historyNote*: | 97
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publicMeSHNote*: | 97
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Scope note: | A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
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activeMeSHYear*: | |
dateCreated*: | 1996-06-19X |
dateEstablished*: | 1997-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | agsX |
recordOriginator*: | ADPX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Sisäsiittoiset MRL lpr -hiiret (fi) XSisäsiittoinen MRL lpr -hiiri (fi, replaced) Möss, inavlade MRL lpr (sv) Mouse, MRL lpr (en, replaced) Mouse, Inbred MRL lpr (en, replaced) Mice, MRL lpr (en, replaced) |
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