ONKI3 | Medical Subject Headings

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Cytochrome P-450 CYP2E1

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 14 coordinate concepts ∟ 7-Alkoxycoumarin O-Dealkylase \| ∟ Aniline Hydroxylase \| ∟ Benzopyrene Hydroxylase \| ∟ Cytochrome P-450 CYP1A1 \| ∟ Cytochrome P-450 CYP1A2 \| ∟ Cytochrome P-450 CYP2B1 \| ∟ Cytochrome P-450 CYP2D6 \| ∟ Cytochrome P-450 CYP3A \| ∟ Aminopyrine N-Demethylase \| ∟ Dihydropteridine Reductase \| ∟ Dimethylglycine Dehydrogenase \| ∟ Ethylmorphine-N-Demethylase \| ∟ Sarcosine Dehydrogenase \| ∟ Sarcosine Oxidase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 14 coordinate concepts ∟ 7-Alkoxycoumarin O-Dealkylase \| ∟ Aniline Hydroxylase \| ∟ Benzopyrene Hydroxylase \| ∟ Cytochrome P-450 CYP1A1 \| ∟ Cytochrome P-450 CYP1A2 \| ∟ Cytochrome P-450 CYP2B1 \| ∟ Cytochrome P-450 CYP2D6 \| ∟ Cytochrome P-450 CYP3A \| ∟ Aminopyrine N-Demethylase \| ∟ Dihydropteridine Reductase \| ∟ Dimethylglycine Dehydrogenase \| ∟ Ethylmorphine-N-Demethylase \| ∟ Sarcosine Dehydrogenase \| ∟ Sarcosine Oxidase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxidoreductases Acting on CH-NH Group Donors ∟ Oxidoreductases, N-Demethylating ∟ Cytochrome P-450 CYP2E1 14 coordinate concepts ∟ 7-Alkoxycoumarin O-Dealkylase \| ∟ Aniline Hydroxylase \| ∟ Benzopyrene Hydroxylase \| ∟ Cytochrome P-450 CYP1A1 \| ∟ Cytochrome P-450 CYP1A2 \| ∟ Cytochrome P-450 CYP2B1 \| ∟ Cytochrome P-450 CYP2D6 \| ∟ Cytochrome P-450 CYP3A \| ∟ Aminopyrine N-Demethylase \| ∟ Dihydropteridine Reductase \| ∟ Dimethylglycine Dehydrogenase \| ∟ Ethylmorphine-N-Demethylase \| ∟ Sarcosine Dehydrogenase \| ∟ Sarcosine Oxidase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 14 coordinate concepts ∟ 7-Alkoxycoumarin O-Dealkylase \| ∟ Aniline Hydroxylase \| ∟ Benzopyrene Hydroxylase \| ∟ Cytochrome P-450 CYP1A1 \| ∟ Cytochrome P-450 CYP1A2 \| ∟ Cytochrome P-450 CYP2B1 \| ∟ Cytochrome P-450 CYP2D6 \| ∟ Cytochrome P-450 CYP3A \| ∟ Aminopyrine N-Demethylase \| ∟ Dihydropteridine Reductase \| ∟ Dimethylglycine Dehydrogenase \| ∟ Ethylmorphine-N-Demethylase \| ∟ Sarcosine Dehydrogenase \| ∟ Sarcosine Oxidase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxidoreductases Acting on CH-NH Group Donors ∟ Oxidoreductases, N-Demethylating ∟ Cytochrome P-450 CYP2E1 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Aryl Hydrocarbon Hydroxylases ∟ Cytochrome P-450 CYP2E1 Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Hemeproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Oxidoreductases, N-Demethylating > Oxidoreductases Acting on CH-NH Group Donors > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 Enzyme System > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Annotation:	do not confuse with other cytochrome P-450 CYP's X
History note:	Cytochrome P-450 (1975-1996) \| Hydroxylases (1984-1996) \| Nitrosamines (1972-1976) \| Oxidoreductases (1972-1974) \| Oxidoreductases, N-Demethylating (1975-1996)X
historyNote*:	97; was DIMETHYLNITROSAMIME N-DEMETHYLASE (NM) 1972-96 & was 4-NITROPHENOL-2-HYDROXYLASE (NM) 1984-96 X
onlineNote*:	use CYTOCHROME P-450 CYP2E1 (NM) to search DIMETHYLNITROSAMINE N-DEMETHYLASE 1980-96 & 4-NITROPHENOL-2-HYDROXYLASE 1984-96 X
publicMeSHNote*:	97; DIMETHYLNITROSAMINE N-DEMETHYLASE was indexed under CYTOCHROME P-450 & OXIDOREDUCTASES, N-DEMETHYLATING 1975-96, NITROSAMINES 1972-76, & OXIDOREDUCTASES 1972-74; 4-NITROPHENOL-2-HYDROXYLASE was indexed under CYTOCHROME P-450 & HYDROXYLASES 1984-96 X
Scope note:	An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include alcohol; NITROSAMINES; BENZENE; URETHANE; and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1996-06-24X
dateEstablished*:	1997-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	ADPX
Type:	Concept X
Coordinate terms:	7-Alkoxycoumarin O-Dealkylase \| Aniline Hydroxylase \| Benzopyrene Hydroxylase \| Cytochrome P-450 CYP1A1 \| Cytochrome P-450 CYP1A2 \| Cytochrome P-450 CYP2B1 \| Cytochrome P-450 CYP2D6 \| Cytochrome P-450 CYP3A \| Aminopyrine N-Demethylase \| Dihydropteridine Reductase \| Dimethylglycine Dehydrogenase \| Ethylmorphine-N-Demethylase \| Sarcosine Dehydrogenase \| Sarcosine Oxidase X
URI:	X
Labels and equivalent concepts:	Sytokromi P-450 CYP2E1 (fi) Cytokrom P-450 CYP2E1 (sv) Cytochrome P-450-J (en, replaced) Cytochrome P450 2E1 (en, replaced) Dimethylnitrosamine N-Demethylase (en, replaced) N-Nitrosodimethylamine Demethylase (en, replaced) Cytochrome P-450 IIE1 (en, replaced) Cytochrome P-450 (ALC) (en, replaced) CYP 2E1 (en, replaced) CYP IIE1 (en, replaced) CYP2E1 (en, replaced) CYPIIE1 (en, replaced) 4-Nitrophenol-2-Hydroxylase (en, replaced) X
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