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The way concept relations are shown:
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid ∟ ∟ ∟ ∟ ∟ ∟ 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid ∟ ∟ ∟ ∟ ∟ ∟ ∟ 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid ∟ ∟ ∟ ∟ ∟ ∟ ∟ 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid X |
Broader terms: | |
Annotation: | DF: note short X ref
X |
History note: | Arachidonic Acids (1975-1984) | Fatty Alcohols (1975-1976) | Hydroxy Acids (1976-1978) | Hydroxyeicosatetraenoic Acids (1985-1996)X |
historyNote*: | 97; was 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID (NM) 1975-96
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onlineNote*: | use 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID (NM) to search 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID 1980-96
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publicMeSHNote*: | 97; 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID was indexed under HYDROXYEICOSATETRAENOIC ACIDS 1985-96, ARACHIDONIC ACIDS 1975-84, HYDROXY ACIDS 1976-80, & FATTY ALCOHOLS 1975-76
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Scope note: | A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
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activeMeSHYear*: | |
dateCreated*: | 1996-06-10X |
dateEstablished*: | 1997-01-01X |
dateRevised*: | 2003-07-09X |
Type: | |
URI: | |
Labels and equivalent concepts: | 12-hydroksi-5,8,10,14-eikosatetraenoidihappo (fi) X12-hydroxi-5,8,10,14-eikosatetraenosyra (sv) 12-S-Hydroxyeicosatetraenoic Acid (en, replaced) 12-HETE (en, replaced) |
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