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The way concept relations are shown:
Buthionine Sulfoximine
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine X |
Broader terms: | ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine ∟ ∟ ∟ ∟ ∟ ∟ Buthionine Sulfoximine |
History note: | Methionine Sulfoximine (1979-1996)X |
historyNote*: | 97: was BUTHIONINE SULFOXIMINE (NM) 1979-96
X |
onlineNote*: | use BUTHIONINE SULFOXIMINE (NM) to search BUTHIONINE SULFOXIMINE 1980-96
X |
publicMeSHNote*: | 97; BUTHIONINE SULFOXIMINE was indexed under METHIONINE SULFOXIMINE 1979-96
X |
Scope note: | A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7)
X |
activeMeSHYear*: | |
dateCreated*: | 1996-06-10X |
dateEstablished*: | 1997-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | ADPX |
Type: | |
URI: | |
Labels and equivalent concepts: | Butioniinisulfoksimiini (fi) XButioninsulfoximin (sv) |
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