ONKI3 | Medical Subject Headings

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Platelet Glycoprotein GPIIb-IIIa Complex

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex 11 coordinate concepts 1 subordinate concept ∟ D019039Q000172* ∟ Integrin alpha6beta4 \| ∟ Receptors, Vitronectin \| ∟ Antigens, CD36 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta1 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex 11 coordinate concepts 1 subordinate concept ∟ D019039Q000172* ∟ Integrin alpha6beta4 \| ∟ Receptors, Vitronectin \| ∟ Antigens, CD36 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta1 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Cytoadhesin ∟ Platelet Glycoprotein GPIIb-IIIa Complex 11 coordinate concepts 1 subordinate concept ∟ D019039Q000172* ∟ Integrin alpha6beta4 \| ∟ Receptors, Vitronectin \| ∟ Antigens, CD36 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta1 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex 11 coordinate concepts 1 subordinate concept ∟ D019039Q000172* ∟ Integrin alpha6beta4 \| ∟ Receptors, Vitronectin \| ∟ Antigens, CD36 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta1 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycoconjugates ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex 11 coordinate concepts 1 subordinate concept ∟ D019039Q000172* ∟ Integrin alpha6beta4 \| ∟ Receptors, Vitronectin \| ∟ Antigens, CD36 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta1 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Receptors, Thrombin X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Cytoadhesin ∟ Platelet Glycoprotein GPIIb-IIIa Complex Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycoconjugates ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Platelet Glycoprotein GPIIb-IIIa Complex Platelet Membrane Glycoproteins > Membrane Glycoproteins > Glycoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Membrane Glycoproteins > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Receptors, Cytoadhesin > Integrins > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Membrane Glycoproteins > Glycoproteins > Glycoconjugates > Carbohydrates > Medical Subject Headings (MeSH) X
Narrower terms:	D019039Q000172* X
History note:	Integrins (1992-1995) \| Platelet Membrane Glycoproteins (1987-1995)X
historyNote*:	1996(1987); use INTEGRIN ALPHAIIBBETA3 (NM) 1992-1995 X
publicMeSHNote*:	1996; see PLATELET MEMBRANE GLYCOPROTEINS 1987-95; INTEGRIN ALPHAIIBBETA3 was indexed under INTEGRINS 1992-95 X
Scope note:	Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1995-05-26X
dateEstablished*:	1996-01-01X
dateRevised*:	2003-07-09X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	AGSX
Related term:	Thrombasthenia X
Type:	Concept X
Coordinate terms:	Integrin alpha6beta4 \| Receptors, Vitronectin \| Antigens, CD36 \| Integrin alpha2beta1 \| Integrin alpha5beta1 \| Integrin alpha6beta1 \| Integrin alphaVbeta3 \| Lysosomal-Associated Membrane Protein 1 \| P-Selectin \| Platelet Glycoprotein GPIb-IX Complex \| Receptors, Thrombin X
URI:	X
Labels and equivalent concepts:	Verihiutaleiden glykoproteiini GPIIb-IIIa-kompleksi (fi) Trombosyyttien glykoproteiini GPIIb-IIIa-kompleksi (fi, replaced) Trombocytglykoprotein GPIIb-IIIa-komplex (sv) Integrin alphaIIbbeta3 (en, replaced) Integrin alpha-IIb beta-3 (en, replaced) GPIIb-IIIa Receptors (en, replaced) Glycoproteins IIb-IIIa (en, replaced) X
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