The way property values are displayed:
The way concept relations are shown:
The way concept relations are shown:
Antineoplastic Agents, Alkylating
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Antineoplastic Agents, Alkylating 8 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Antineoplastic Agents, Alkylating 8 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Antineoplastic Agents, Alkylating 8 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
History note: | |
historyNote*: | 96
X |
publicMeSHNote*: | 96
X |
Scope note: | A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
X |
activeMeSHYear*: | |
dateCreated*: | 1995-05-26X |
dateEstablished*: | 1996-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | JRTX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Alkyloivat solunsalpaajat (fi) XAlkyloiva syöpälääke (fi, replaced) Alkyloiva solunsalpaaja (fi, replaced) Alkyloiva sytostaatti (fi, replaced) Alkyloivat aineet (fi, replaced) Alkyloivat sytostaatit (fi, replaced) Alkyloivat syöpälääkkeet (fi, replaced) Alkyloiva aine (fi, replaced) Alkylerande cellgifter (sv) Antineoplastics, Alkylating (en, replaced) Alkylating Antineoplastic Drugs (en, replaced) Alkylating Antineoplastic Agents (en, replaced) Alkylating Antineoplastics (en, replaced) Alkylating Drugs, Antineoplastic (en, replaced) Antineoplastic Drugs, Alkylating (en, replaced) Antineoplastic Alkylating Agents (en, replaced) Alkylating Agents, Antineoplastic (en, replaced) |
Share: |
Loading results...