ONKI3 | Medical Subject Headings

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Multiple Endocrine Neoplasia Type 2b

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Neoplastic Syndromes, Hereditary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b 2 coordinate concepts ∟ Multiple Endocrine Neoplasia Type 1 \| ∟ Multiple Endocrine Neoplasia Type 2a Medical Subject Headings (MeSH) ∟ Endocrine System Diseases ∟ Endocrine Gland Neoplasms ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b 2 coordinate concepts ∟ Multiple Endocrine Neoplasia Type 1 \| ∟ Multiple Endocrine Neoplasia Type 2a Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplasms by Site ∟ Endocrine Gland Neoplasms ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b 2 coordinate concepts ∟ Multiple Endocrine Neoplasia Type 1 \| ∟ Multiple Endocrine Neoplasia Type 2a Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplasms, Multiple Primary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b 2 coordinate concepts ∟ Multiple Endocrine Neoplasia Type 1 \| ∟ Multiple Endocrine Neoplasia Type 2a Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplastic Syndromes, Hereditary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b 2 coordinate concepts ∟ Multiple Endocrine Neoplasia Type 1 \| ∟ Multiple Endocrine Neoplasia Type 2a X
Broader terms:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Neoplastic Syndromes, Hereditary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b Medical Subject Headings (MeSH) ∟ Endocrine System Diseases ∟ Endocrine Gland Neoplasms ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplasms by Site ∟ Endocrine Gland Neoplasms ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplasms, Multiple Primary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b Medical Subject Headings (MeSH) ∟ Neoplasms ∟ Neoplastic Syndromes, Hereditary ∟ Multiple Endocrine Neoplasia ∟ Multiple Endocrine Neoplasia Type 2b Multiple Endocrine Neoplasia > Neoplastic Syndromes, Hereditary > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Multiple Endocrine Neoplasia > Endocrine Gland Neoplasms > Endocrine System Diseases > Medical Subject Headings (MeSH) Multiple Endocrine Neoplasia > Endocrine Gland Neoplasms > Neoplasms by Site > Neoplasms > Medical Subject Headings (MeSH) Multiple Endocrine Neoplasia > Neoplasms, Multiple Primary > Neoplasms > Medical Subject Headings (MeSH) Multiple Endocrine Neoplasia > Neoplastic Syndromes, Hereditary > Neoplasms > Medical Subject Headings (MeSH) X
Annotation:	coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent X
History note:	Multiple Endocrine Neoplasia (1975-1994)X
historyNote*:	95; MEA III & MEN III were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94 X
onlineNote*:	use MULTIPLE ENDOCRINE NEOPLASIA to search MEA III & MEN III 1983-94 X
publicMeSHNote*:	95; MEA III & MEN III were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94 X
Scope note:	Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1994-05-23X
dateEstablished*:	1995-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	AGSX
Type:	Concept X
Coordinate terms:	Multiple Endocrine Neoplasia Type 1 \| Multiple Endocrine Neoplasia Type 2a X
URI:	X
Labels and equivalent concepts:	MEN 2B -oireyhtymä (fi) MEN-2B (fi, replaced) MEN-2b (fi, replaced) MEN 2b -syndrooma (fi, replaced) MEN 2B -syndrooma (fi, replaced) MEN 2b -oireyhtymä (fi, replaced) MEN2b (fi, replaced) Monikasvainoireyhtymä 2B (fi, replaced) Multippeli endokriininen neoplasia tyyppi 2b (fi, replaced) Multippeli endokriininen neoplasia tyyppi 2B (fi, replaced) Monikasvainoireyhtymä 2b (fi, replaced) MEN 2b (fi, replaced) MEN 2B (fi, replaced) Multipla hormonella tumörer typ 2b (sv) Multipel endokrin neoplasi typ 2b (sv, replaced) MEN IIb (en, replaced) MEN 3 (en, replaced) MEN 2b (en, replaced) MEA IIb (en, replaced) MEN III (en, replaced) MEN2b (en, replaced) Neoplasms, Multiple Endocrine Type 2b (en, replaced) Neoplasia, Multiple Endocrine Type 2b (en, replaced) Multiple Endocrine Neoplasms Type 2b (en, replaced) Mucosal Neuroma Syndrome (en, replaced) MEA 2b (en, replaced) X
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