ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 17 coordinate concepts 2 subordinate concepts ∟ Interleukin-12 Subunit p35 \| ∟ Interleukin-12 Subunit p40 ∟ Interleukin-1 \| ∟ Interleukin-10 \| ∟ Interleukin-11 \| ∟ Interleukin-13 \| ∟ Interleukin-15 \| ∟ Interleukin-16 \| ∟ Interleukin-17 \| ∟ Interleukin-18 \| ∟ Interleukin-2 \| ∟ Interleukin-23 \| ∟ Interleukin-3 \| ∟ Interleukin-4 \| ∟ Interleukin-5 \| ∟ Interleukin-6 \| ∟ Interleukin-7 \| ∟ Interleukin-8 \| ∟ Interleukin-9 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 17 coordinate concepts 2 subordinate concepts ∟ Interleukin-12 Subunit p35 \| ∟ Interleukin-12 Subunit p40 ∟ Interleukin-1 \| ∟ Interleukin-10 \| ∟ Interleukin-11 \| ∟ Interleukin-13 \| ∟ Interleukin-15 \| ∟ Interleukin-16 \| ∟ Interleukin-17 \| ∟ Interleukin-18 \| ∟ Interleukin-2 \| ∟ Interleukin-23 \| ∟ Interleukin-3 \| ∟ Interleukin-4 \| ∟ Interleukin-5 \| ∟ Interleukin-6 \| ∟ Interleukin-7 \| ∟ Interleukin-8 \| ∟ Interleukin-9 Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 17 coordinate concepts 2 subordinate concepts ∟ Interleukin-12 Subunit p35 \| ∟ Interleukin-12 Subunit p40 ∟ Interleukin-1 \| ∟ Interleukin-10 \| ∟ Interleukin-11 \| ∟ Interleukin-13 \| ∟ Interleukin-15 \| ∟ Interleukin-16 \| ∟ Interleukin-17 \| ∟ Interleukin-18 \| ∟ Interleukin-2 \| ∟ Interleukin-23 \| ∟ Interleukin-3 \| ∟ Interleukin-4 \| ∟ Interleukin-5 \| ∟ Interleukin-6 \| ∟ Interleukin-7 \| ∟ Interleukin-8 \| ∟ Interleukin-9 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Intercellular Signaling Peptides and Proteins ∟ Cytokines ∟ Interleukins ∟ Interleukin-12 Interleukins > Cytokines > Intercellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Interleukins > Cytokines > Intercellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Interleukins > Cytokines > Intercellular Signaling Peptides and Proteins > Biological Factors > Medical Subject Headings (MeSH) X
Narrower terms:	Interleukin-12 Subunit p35 \| Interleukin-12 Subunit p40 X
Annotation:	DF: IL 12 or IL12 X
History note:	Interleukins (1991-1994)X
historyNote*:	1995(1995) X
publicMeSHNote*:	1995; INTERLEUKIN 12 was indexed under INTERLEUKINS 1991-1994; INTERLEUKIN-12 P70 was indexed under INTERLEUKIN-12 2003-2006 X
Scope note:	A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. X
activeMeSHYear*:	2007X
dateCreated*:	1994-04-19X
dateEstablished*:	1995-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	AGSX
Related term:	Immunity, Cellular X
Type:	Concept X
Coordinate terms:	Interleukin-1 \| Interleukin-10 \| Interleukin-11 \| Interleukin-13 \| Interleukin-15 \| Interleukin-16 \| Interleukin-17 \| Interleukin-18 \| Interleukin-2 \| Interleukin-23 \| Interleukin-3 \| Interleukin-4 \| Interleukin-5 \| Interleukin-6 \| Interleukin-7 \| Interleukin-8 \| Interleukin-9 X
URI:	X
Labels and equivalent concepts:	Interleukiini-12 (fi) IL-12 (fi, replaced) Interleukiini 12 (fi, replaced) Interleukin-12 p70 (en, replaced) Natural Killer Cell Stimulatory Factor (en, replaced) Interleukin 12 (en, replaced) IL12 (en, replaced) Edodekin Alfa (en, replaced) IL 12 (en, replaced) IL-12 (en, replaced) IL-12 p70 (en, replaced) Cytotoxic Lymphocyte Maturation Factor (en, replaced) X
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