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Patch-Clamp Techniques
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Annotation: | a cytol technique for removing a tiny patch of plasma membrane; NIM
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historyNote*: | 95
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publicMeSHNote*: | 95
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Scope note: | An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
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activeMeSHYear*: | |
dateCreated*: | 1994-01-25X |
dateEstablished*: | 1995-01-01X |
dateRevised*: | 2000-06-22X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | TGCX |
recordOriginator*: | PXPX |
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Labels and equivalent concepts: | Patch-clamp-menetelmät (fi) XPatch-clamp-tekniikka (fi, replaced) Patch-clamp-tekniikat (fi, replaced) Patch-clamp-menetelmä (fi, replaced) Voltage-Clamp Technics (en, replaced) Patch-Clamp Technics (en, replaced) |
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