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Leukotriene A4
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Leukotriene A4 3 coordinate conceptsX |
Broader terms: | |
Annotation: | /biosyn /physiol permitted
X |
History note: | |
historyNote*: | 94; was LEUKOTRIENE A (NM) 1980-93
X |
onlineNote*: | use LEUKOTRIENE A4 (NM) to search LEUKOTRIENE A 1980-93
X |
publicMeSHNote*: | 94; LEUKOTRIENE A was indexed under LEUKOTRIENES 1989-93 & ARACHIDONIC ACIDS 1980-88
X |
Scope note: | (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
X |
activeMeSHYear*: | |
dateCreated*: | 1993-06-04X |
dateEstablished*: | 1994-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | TPWX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Leukotrieeni A4 (fi) XLeukotrien A4 (sv) LTA4 (en, replaced) Leukotrienes A (en, replaced) Leukotriene A-4 (en, replaced) |
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