ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Biological Phenomena, Cell Phenomena, and Immunity ∟ Cell Physiology ∟ Cell Death ∟ Apoptosis 2 coordinate concepts 1 subordinate concept ∟ Anoikis ∟ Autophagy \| ∟ Necrosis Medical Subject Headings (MeSH) ∟ Physiological Processes ∟ Cell Physiology ∟ Cell Death ∟ Apoptosis 2 coordinate concepts 1 subordinate concept ∟ Anoikis ∟ Autophagy \| ∟ Necrosis X
Broader terms:	Medical Subject Headings (MeSH) ∟ Biological Phenomena, Cell Phenomena, and Immunity ∟ Cell Physiology ∟ Cell Death ∟ Apoptosis Medical Subject Headings (MeSH) ∟ Physiological Processes ∟ Cell Physiology ∟ Cell Death ∟ Apoptosis Cell Death > Cell Physiology > Biological Phenomena, Cell Phenomena, and Immunity > Medical Subject Headings (MeSH) Cell Death > Cell Physiology > Physiological Processes > Medical Subject Headings (MeSH) X
Narrower terms:	Anoikis X
Annotation:	do not confuse with NECROSIS, pathological cell death; unspecified probably goes here; PROGRAMMED CELL DEATH, TYPE II see AUTOPHAGY is also available X
History note:	Cell Survival (1972-1992)X
historyNote*:	93 X
publicMeSHNote*:	93 X
Scope note:	One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. X
activeMeSHYear*:	2007X
dateCreated*:	1992-05-07X
dateEstablished*:	1993-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	MXRX
Related term:	CARD Signaling Adaptor Proteins \| Caspases \| Cellular Apoptosis Susceptibility Protein \| Death Domain Receptor Signaling Adaptor Proteins \| Genes, Transgenic, Suicide \| In Situ Nick-End Labeling \| Necrosis X
Type:	Concept X
Coordinate terms:	Autophagy \| Necrosis X
URI:	X
Labels and equivalent concepts:	Ohjelmoitunut solukuolema (fi) Apoptoosi (fi, replaced) Apoptos (sv) Programmerad celldöd (sv, replaced) Programmed Cell Death, Type I (en, replaced) Apoptosis (la-FI, replaced) X
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