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Prion Diseases
Hierarchy: | ∟ ∟ ∟ Prion Diseases 24 coordinate concepts7 subordinate concepts∟ ∟ ∟ ∟ Prion Diseases 24 coordinate concepts7 subordinate concepts∟ ∟ ∟ Prion Diseases 24 coordinate concepts7 subordinate conceptsX |
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Annotation: | GEN or unspecified: prefer specifics
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History note: | Slow Virus Diseases (1966-1992)X |
historyNote*: | 1993
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publicMeSHNote*: | 1993
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Scope note: | A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
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activeMeSHYear*: | |
dateCreated*: | 1992-05-22X |
dateEstablished*: | 1993-01-01X |
dateRevised*: | 2005-07-13X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | AGSX |
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Labels and equivalent concepts: | Prionisairaudet (fi) XPrionitaudit (fi, replaced) Prionsjukdomar (sv) Transmissible Dementias (en, replaced) Transmissible Spongiform Encephalopathies (en, replaced) Spongiform Encephalopathies, Transmissible (en, replaced) Prion-Induced Disorder (en, replaced) Encephalopathies, Spongiform, Transmissible (en, replaced) Inherited Human Transmissible Spongiform Encephalopathies (en, replaced) Prion Protein Diseases (en, replaced) Dementias, Transmissible (en, replaced) |
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