ONKI3 | Medical Subject Headings

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The way concept relations are shown: separately in hierarchy

Lupus Coagulation Inhibitor

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor 4 coordinate concepts ∟ Antibodies, Anticardiolipin \| ∟ Antithrombin III \| ∟ Protein C \| ∟ Protein S Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Serum Globulins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor 4 coordinate concepts ∟ Antibodies, Anticardiolipin \| ∟ Antithrombin III \| ∟ Protein C \| ∟ Protein S Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Globulins ∟ Serum Globulins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor 4 coordinate concepts ∟ Antibodies, Anticardiolipin \| ∟ Antithrombin III \| ∟ Protein C \| ∟ Protein S Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Blood Coagulation Factor Inhibitors ∟ Lupus Coagulation Inhibitor 4 coordinate concepts ∟ Antibodies, Anticardiolipin \| ∟ Antithrombin III \| ∟ Protein C \| ∟ Protein S X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Serum Globulins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Globulins ∟ Serum Globulins ∟ Immunoglobulins ∟ Antibodies ∟ Autoantibodies ∟ Antibodies, Antiphospholipid ∟ Lupus Coagulation Inhibitor Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Blood Coagulation Factor Inhibitors ∟ Lupus Coagulation Inhibitor Antibodies, Antiphospholipid > Autoantibodies > Antibodies > Immunoglobulins > Immunoproteins > Blood Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Antibodies, Antiphospholipid > Autoantibodies > Antibodies > Immunoglobulins > Serum Globulins > Blood Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Antibodies, Antiphospholipid > Autoantibodies > Antibodies > Immunoglobulins > Serum Globulins > Globulins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Blood Coagulation Factor Inhibitors > Biological Factors > Medical Subject Headings (MeSH) X
Annotation:	DF: LUPUS COAG INHIB X
History note:	Autoantibodies (1966-1991) \| Blood Coagulation Factors (1966-1991)X
historyNote*:	92; was LUPUS COAGULATION INHIBITOR (NM) 1978-91 X
onlineNote*:	use LUPUS COAGULATION INHIBITOR (NM) to search LUPUS COAGULATION INHIBITOR 1980-91 X
publicMeSHNote*:	92; LUPUS COAGULATION INHIBITOR was indexed under BLOOD COAGULATION FACTORS/immunology 1986-91 & BLOOD COAGULATION FACTORS/antagonists & inhibitors 1978-88 X
Scope note:	An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications. X
activeMeSHYear*:	2006 \| 2006A \| 2007X
dateCreated*:	1991-07-12X
dateEstablished*:	1992-01-01X
dateRevised*:	2005-07-19X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	RLSX
Related term:	Antiphospholipid Syndrome X
Type:	Concept X
Coordinate terms:	Antibodies, Anticardiolipin \| Antithrombin III \| Protein C \| Protein S X
URI:	X
Labels and equivalent concepts:	Lupusantikoagulantti (fi) Lupuskoagulationshämmare (sv) Lupusantikoagulant (sv, replaced) Lupus Anticoagulant (en, replaced) Inhibitor, Lupus Coagulation (en, replaced) Coagulation Inhibitor, Lupus (en, replaced) Anticoagulant, Lupus (en, replaced) X
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