ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Fusion Proteins, bcr-abl

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Mutant Proteins ∟ Mutant Chimeric Proteins ∟ Oncogene Proteins, Fusion ∟ Fusion Proteins, bcr-abl 6 coordinate concepts ∟ Fusion Proteins, gag-onc \| ∟ Oncogene Protein tpr-met \| ∟ Autocrine Motility Factor \| ∟ Myeloma Proteins \| ∟ Oncogene Proteins \| ∟ Tumor Suppressor Proteins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Neoplasm Proteins ∟ Fusion Proteins, bcr-abl 6 coordinate concepts ∟ Fusion Proteins, gag-onc \| ∟ Oncogene Protein tpr-met \| ∟ Autocrine Motility Factor \| ∟ Myeloma Proteins \| ∟ Oncogene Proteins \| ∟ Tumor Suppressor Proteins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Neoplasm Proteins ∟ Oncogene Proteins ∟ Oncogene Proteins, Fusion ∟ Fusion Proteins, bcr-abl 6 coordinate concepts ∟ Fusion Proteins, gag-onc \| ∟ Oncogene Protein tpr-met \| ∟ Autocrine Motility Factor \| ∟ Myeloma Proteins \| ∟ Oncogene Proteins \| ∟ Tumor Suppressor Proteins X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Mutant Proteins ∟ Mutant Chimeric Proteins ∟ Oncogene Proteins, Fusion ∟ Fusion Proteins, bcr-abl Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Neoplasm Proteins ∟ Fusion Proteins, bcr-abl Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Neoplasm Proteins ∟ Oncogene Proteins ∟ Oncogene Proteins, Fusion ∟ Fusion Proteins, bcr-abl Oncogene Proteins, Fusion > Mutant Chimeric Proteins > Mutant Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Neoplasm Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Oncogene Proteins, Fusion > Oncogene Proteins > Neoplasm Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
Annotation:	IM; found in various leukemias: coord IM with specific leukemia (IM); /drug eff /ultrastruct permitted X
History note:	Neoplasm Proteins (1986-1989)X
historyNote*:	91; was BCR-ABL FUSION PROTEINS 1990 X
onlineNote*:	use FUSION PROTEINS, BCR-ABL to search BCR-ABL FUSION PROTEINS 1990 X
publicMeSHNote*:	91; was BCR-ABL FUSION PROTEINS 1990 X
Scope note:	Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in Abelson murine leukemia virus. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1989-05-25X
dateEstablished*:	1990-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	nnsX
recordOriginator*:	AGSX
Related term:	Philadelphia Chromosome X
Type:	Concept X
Coordinate terms:	Fusion Proteins, gag-onc \| Oncogene Protein tpr-met \| Autocrine Motility Factor \| Myeloma Proteins \| Oncogene Proteins \| Tumor Suppressor Proteins X
URI:	X
Labels and equivalent concepts:	Bcr-abl-fuusioproteiinit (fi) Bcr-abl-fuusioproteiini (fi, replaced) Fusionsproteiner, bcr-abl (sv) bcr-abl Fusion Proteins (en, replaced) X
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