ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Receptors, Leukocyte-Adhesion

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Leukocyte-Adhesion 7 coordinate concepts 3 subordinate concepts ∟ Integrin alphaXbeta2 \| ∟ Lymphocyte Function-Associated Antigen-1 \| ∟ Macrophage-1 Antigen ∟ Integrin alpha Chains \| ∟ Integrin beta Chains \| ∟ Receptors, Cytoadhesin \| ∟ Receptors, Fibrinogen \| ∟ Receptors, Fibronectin \| ∟ Receptors, Very Late Antigen \| ∟ Receptors, Vitronectin X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Leukocyte-Adhesion Integrins > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
Narrower terms:	Integrin alphaXbeta2 \| Lymphocyte Function-Associated Antigen-1 \| Macrophage-1 Antigen X
Annotation:	/defic: consider LEUKOCYTE-ADHESION DEFICIENCY SYNDROME; DF: RECEPT LEUKOCYTE ADHESION X
History note:	Antigens (1966-1987) \| Antigens, Differentiation (1988-1989) \| Receptors, Cell Surface (1973-1989) \| Receptors, Immunologic (1980-1989)X
historyNote*:	90 X
publicMeSHNote*:	90 X
Scope note:	Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1989-07-07X
dateEstablished*:	1990-01-01X
dateRevised*:	2003-07-09X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	RLSX
Related term:	Leukocyte-Adhesion Deficiency Syndrome X
Type:	Concept X
Coordinate terms:	Integrin alpha Chains \| Integrin beta Chains \| Receptors, Cytoadhesin \| Receptors, Fibrinogen \| Receptors, Fibronectin \| Receptors, Very Late Antigen \| Receptors, Vitronectin X
URI:	X
Labels and equivalent concepts:	Valkosoluadheesioreseptorit (fi) Leukosyyttiadheesioreseptorit (fi, replaced) Valkosoluadheesioreseptori (fi, replaced) Leukosyyttiadheesioreseptori (fi, replaced) Leukocyte-Adhesion Receptors (en, replaced) Leukocyte-Adhesion Receptor (en, replaced) Leukocyte-Adhesion Receptor Family (en, replaced) Leu-CAM Receptor Family (en, replaced) X
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