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Giant Cells
Hierarchy: | ∟ ∟ Giant Cells 34 coordinate concepts2 subordinate conceptsX |
Broader terms: | |
Narrower terms: | |
Annotation: | any very large cell; A 11 qualif
X |
History note: | Cell Fusion (1972-1989)X |
historyNote*: | 90
X |
publicMeSHNote*: | 90
X |
Scope note: | Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
X |
activeMeSHYear*: | |
dateCreated*: | 1989-04-07X |
dateEstablished*: | 1990-01-01X |
dateRevised*: | 1996-06-10X |
recordAuthorizer*: | PLSX |
recordMaintainer*: | TGCX |
recordOriginator*: | AGSX |
Type: | |
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Labels and equivalent concepts: | Jättisolut (fi) XJättisolu (fi, replaced) Jätteceller (sv) Syncytium (en, replaced) Syncytia (en, replaced) Polykaryocytes (en, replaced) Multinucleated Giant Cells (en, replaced) Giant Cells, Multinucleated (en, replaced) |
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