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Osteocalcin
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History note: | 1-Carboxyglutamic Acid (1978-1981) | Binding Proteins (1978-1980) | Calcium (1978-1980) | Calcium-Binding Proteins (1980-1989) | Proteins (1980-1981)X |
historyNote*: | 90; GLA-PROTEIN was see OSTEOCACLIN 1990-96
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onlineNote*: | use OSTEOCALCIN to search GLA-PROTEIN 1990-96
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publicMeSHNote*: | 90; GLA-PROTEIN was see OSTEOCALCIN 1990-96
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Scope note: | Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
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activeMeSHYear*: | |
dateCreated*: | 1989-09-06X |
dateEstablished*: | 1990-01-01X |
dateRevised*: | 2004-07-07X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | AGSX |
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Labels and equivalent concepts: | Osteokalsiini (fi) XGLA-proteiini (fi, replaced) Osteokalcin (sv) Vitamin K-Dependent Bone Protein (en, replaced) Gla Protein, Bone (en, replaced) Calcium-Binding Protein, Vitamin K-Dependent (en, replaced) Bone gamma-Carboxyglutamic Acid Protein (en, replaced) Bone Gla Protein (en, replaced) 4-Carboxyglutamic Protein, Bone (en, replaced) |
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