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Oligonucleotide Probes
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Annotation: | usually no qualif; /drug eff /ultrastruct permitted
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historyNote*: | 89
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publicMeSHNote*: | 89
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Scope note: | Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
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activeMeSHYear*: | |
dateCreated*: | 1988-06-01X |
dateEstablished*: | 1989-01-01X |
dateRevised*: | 2003-07-09X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | EJBX |
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Labels and equivalent concepts: | Oligonukleotidikoettimet (fi) XOligonukleotidikoetin (fi, replaced) Oligonukleotidsonder (sv) |
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