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DNA Probes
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ DNA Probes 3 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ DNA Probes 3 coordinate concepts4 subordinate conceptsX |
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Annotation: | GEN or unspecified; prefer specifics; /drug eff /ultrastruct permitted; CDNA PROBES see DNA, COMPLEMENTARY is also available
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historyNote*: | 89
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publicMeSHNote*: | 89
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Scope note: | Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
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activeMeSHYear*: | |
dateCreated*: | 1988-06-01X |
dateEstablished*: | 1989-01-01X |
dateRevised*: | 2005-07-27X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | EJBX |
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Labels and equivalent concepts: | DNA-koettimet (fi) XDNA-koetin (fi, replaced) DNA-sonder (sv) DNA Hybridization Probes (en, replaced) |
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