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Dideoxynucleosides
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Dideoxynucleosides 6 coordinate concepts5 subordinate concepts∟ ∟ ∟ ∟ Dideoxynucleosides 6 coordinate concepts5 subordinate conceptsX |
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Annotation: | antivirals & antimetabolites
X |
History note: | Deoxyribonucleosides (1971-1988)X |
historyNote*: | 89
X |
publicMeSHNote*: | 89
X |
Scope note: | Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
X |
activeMeSHYear*: | |
dateCreated*: | 1988-05-12X |
dateEstablished*: | 1989-01-01X |
dateRevised*: | 1995-06-08X |
recordAuthorizer*: | PLSX |
recordMaintainer*: | JRTX |
recordOriginator*: | RLSX |
Type: | |
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Labels and equivalent concepts: | Dideoksinukleosidit (fi) XDideoksinukleosidi (fi, replaced) Dideoxinukleosider (sv) ddNus (en, replaced) |
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