ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Lactones ∟ Spironolactone 12 coordinate concepts ∟ Cortisone \| ∟ Dimethisterone \| ∟ Ethisterone \| ∟ Pregnenediones \| ∟ Pregnenolone \| ∟ 4-Butyrolactone \| ∟ Dehydroascorbic Acid \| ∟ Macrolides \| ∟ Picrotoxin \| ∟ Propiolactone \| ∟ Venturicidins \| ∟ Zearalenone Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Steroids ∟ Pregnanes ∟ Pregnenes ∟ Spironolactone 12 coordinate concepts ∟ Cortisone \| ∟ Dimethisterone \| ∟ Ethisterone \| ∟ Pregnenediones \| ∟ Pregnenolone \| ∟ 4-Butyrolactone \| ∟ Dehydroascorbic Acid \| ∟ Macrolides \| ∟ Picrotoxin \| ∟ Propiolactone \| ∟ Venturicidins \| ∟ Zearalenone X
Broader terms:	Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Lactones ∟ Spironolactone Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Steroids ∟ Pregnanes ∟ Pregnenes ∟ Spironolactone Lactones > Organic Chemicals > Medical Subject Headings (MeSH) Pregnenes > Pregnanes > Steroids > Polycyclic Compounds > Medical Subject Headings (MeSH) X
Scope note:	A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827) X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1999-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	CCRX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	Cortisone \| Dimethisterone \| Ethisterone \| Pregnenediones \| Pregnenolone \| 4-Butyrolactone \| Dehydroascorbic Acid \| Macrolides \| Picrotoxin \| Propiolactone \| Venturicidins \| Zearalenone X
URI:	X
Labels and equivalent concepts:	Spironolaktoni (fi) Spironolakton (sv) Aldactone (sv, replaced) Pharmafrid Brand of Spironolactone (en, replaced) Roche Brand of Spironolactone (en, replaced) Pharmacia Spain Brand of Spironolactone (en, replaced) Pharmacia Brand of Spironolactone (en, replaced) Novopharm Brand of Spironolactone (en, replaced) Searle Brand of Spironolactone (en, replaced) Spirolactone (en, replaced) Wörwag Brand of Spironolactone (en, replaced) Verospirone (en, replaced) Veroshpiron (en, replaced) Mundogen Brand of Spironolactone (en, replaced) Merck dura Brand of Spironolactone (en, replaced) Azupharma Brand of Spironolactone (en, replaced) betapharm Brand of Spironolactone (en, replaced) Ashbourne Brand of Spironolactone (en, replaced) Alter Brand of Spironolactone (en, replaced) Alpharma Brand of Spironolactone (en, replaced) Cardel Brand of Spironolactone (en, replaced) ct-Arzneimittel Brand of Spironolactone (en, replaced) Jenapharm Brand of Spironolactone (en, replaced) Mayoly-Spindler Brand of Spironolactone (en, replaced) Hormosan Brand of Spironolactone (en, replaced) Generosan Brand of Spironolactone (en, replaced) Dexo Brand of Spironolactone (en, replaced) Alphapharm Brand of Spironolactone (en, replaced) Spironolactonum (la-FI, replaced) X
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