ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Lipoprotein ∟ Receptors, LDL 3 subordinate concepts ∟ LDL-Receptor Related Proteins \| ∟ Receptors, Oxidized LDL \| ∟ Receptors, Scavenger X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Lipoprotein ∟ Receptors, LDL Receptors, Lipoprotein > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
Narrower terms:	LDL-Receptor Related Proteins \| Receptors, Oxidized LDL \| Receptors, Scavenger X
Annotation:	DF: RECEPT LDL X
History note:	Lipoproteins, LDL (1972-1984) \| Receptors, Endogenous Substances (1973-1984)X
historyNote*:	85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92 X
onlineNote*:	use RECEPTORS, LDL to search LIPOPROTEINS, LDL RECEPTORS 1985-92 X
publicMeSHNote*:	85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92 X
Scope note:	Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking. X
activeMeSHYear*:	2007X
dateCreated*:	1984-05-25X
dateEstablished*:	1985-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	RLSX
Related term:	Lipoproteins, LDL X
Type:	Concept X
URI:	X
Labels and equivalent concepts:	LDL-reseptorit (fi) LDL-reseptori (fi, replaced) LDL-receptorer (sv) Receptorer, LDL (sv, replaced) Receptors, Lipoprotein, LDL (en, replaced) Receptors, Low Density Lipoprotein (en, replaced) Low Density Lipoprotein Receptors (en, replaced) Low Density Lipoprotein Receptor (en, replaced) LDL Receptors (en, replaced) LDL Receptors, Lipoprotein (en, replaced) Lipoprotein LDL Receptors (en, replaced) LDL Receptor (en, replaced) X
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