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Protein Kinase C
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Protein Kinase C 23 coordinate concepts3 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
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History note: | Protein Kinases (1973-1985)X |
historyNote*: | 86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93
X |
publicMeSHNote*: | 86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93
X |
Scope note: | An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
X |
activeMeSHYear*: | |
dateCreated*: | 1985-05-17X |
dateEstablished*: | 1986-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | RLSX |
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Labels and equivalent concepts: | Proteiinikinaasi C (fi) XProteinkinas C (sv) PKC Serine-Threonine Kinase (en, replaced) Phospholipid-Sensitive Calcium-Dependent Protein Kinase (en, replaced) Calcium-Activated Phospholipid-Dependent Kinase (en, replaced) Calcium Phospholipid-Dependent Protein Kinase (en, replaced) |
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