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Phosphofructokinase-1
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Annotation: | GEN or unspecified; prefer specifics
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historyNote*: | 2002
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publicMeSHNote*: | 2002; see 6-PHOSPHOFRUCTOKINASE 1993-2001, see PHOSPHOFRUCTOKINASE 1965-1992
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Scope note: | An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, C TYPE; found in platelets, brain, and other tissues.
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activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1965-01-01X |
dateRevised*: | 2005-07-08X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Fosfofruktokinaasi 1 (fi) X6-fosfofruktokinaasi (fi, replaced) 6-fosfofruktokinas (sv) Fructose-6-phosphate 1-Phosphotransferase (en, replaced) Fructose-6-P 1-Kinase (en, replaced) 6-Phosphofructokinase (en, replaced) 6-Phosphofructo-1-kinase (en, replaced) |
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