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Myasthenia Gravis
Hierarchy: | ∟ ∟ ∟ ∟ Myasthenia Gravis 10 coordinate concepts2 subordinate concepts∟ ∟ ∟ Myasthenia Gravis 10 coordinate concepts2 subordinate concepts∟ ∟ ∟ ∟ Myasthenia Gravis 10 coordinate concepts2 subordinate conceptsX |
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Annotation: | "myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congen consider MYASTHENIC SYNDROMES, CONGENITAL or specifics
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Scope note: | A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
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activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateRevised*: | 1999-11-08X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | KEVX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | MG (fi, replaced) XMyasthenia gravis (la-FI, replaced) |
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