ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Leukodystrophy, Globoid Cell

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Demyelinating Diseases ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Lipid Metabolism Disorders ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell 11 coordinate concepts ∟ Adrenoleukodystrophy \| ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Fabry Disease \| ∟ Gangliosidoses \| ∟ Gaucher Disease \| ∟ Niemann-Pick Diseases \| ∟ Sea-Blue Histiocyte Syndrome \| ∟ Sulfatidosis X
Broader terms:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Demyelinating Diseases ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Lipid Metabolism Disorders ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Leukodystrophy, Globoid Cell Hereditary Central Nervous System Demyelinating Diseases > Heredodegenerative Disorders, Nervous System > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Sphingolipidoses > Lipidoses > Lipid Metabolism, Inborn Errors > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Lysosomal Storage Diseases > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Brain Diseases > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Hereditary Central Nervous System Demyelinating Diseases > Demyelinating Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Hereditary Central Nervous System Demyelinating Diseases > Heredodegenerative Disorders, Nervous System > Neurodegenerative Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Sphingolipidoses > Lipidoses > Lipid Metabolism Disorders > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Sphingolipidoses > Lipidoses > Lipid Metabolism, Inborn Errors > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Lysosomal Storage Diseases > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) X
historyNote*:	1974(1963) X
publicMeSHNote*:	1974; see CEREBRAL SCLEROSIS, DIFFUSE 1963-1973; for LEUKODYSTROPHIES see CEREBRAL SCLEROSIS, DIFFUSE 1963-1973; for KRABBE DISEASE see KRABBE'S DISEASE 1974-1997 X
Scope note:	An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses. X
activeMeSHYear*:	2007X
dateCreated*:	1999-01-01X
dateEstablished*:	1974-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	NLMX
Related term:	Galactosylceramidase X
Type:	Concept X
Coordinate terms:	Adrenoleukodystrophy \| Alexander Disease \| Canavan Disease \| Leukodystrophy, Metachromatic \| Pelizaeus-Merzbacher Disease \| Fabry Disease \| Gangliosidoses \| Gaucher Disease \| Niemann-Pick Diseases \| Sea-Blue Histiocyte Syndrome \| Sulfatidosis X
URI:	X
Labels and equivalent concepts:	Krabben tauti (fi) Leukodystrofi, globoidcell (sv) Krabbes sjukdom (sv, replaced) Globoidcellsleukodystrofi (sv, replaced) GLD (sv, replaced) Leukodystrophy, Globoid Cell, Infantile (en, replaced) Leukodystrophy, Globoid Cell, Early-Onset (en, replaced) Leukodystrophy, Globoid Cell, Classic (en, replaced) Krabbe's Leukodystrophy (en, replaced) Leukodystrophy, Globoid Cell, Late-Onset (en, replaced) Krabbe's Disease (en, replaced) Krabbe Leukodystrophy (en, replaced) Galactosylceramide-beta-Galactosidase Deficiency Disease (en, replaced) Galactosylceramidase Deficiency Disease (en, replaced) Diffuse Globoid Body Sclerosis (en, replaced) Globoid Body Sclerosis, Diffuse (en, replaced) Globoid Cell Leukodystrophy (en, replaced) Krabbe Disease (en, replaced) Infantile Globoid Cell Leukodystrophy (en, replaced) Globoid Leukodystrophy (en, replaced) Classic Globoid Cell Leukodystrophy (en, replaced) Morbus Krabbe (la-FI, replaced) X
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