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Kernicterus
Hierarchy: | ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus |
Scope note: | A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | NLMX |
Type: | |
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Labels and equivalent concepts: | Kernikterus (fi) XIkterus, kern- (fi, replaced) Kernikterus (sv) Hyperbilirubinemic Encephalopathy (en, replaced) Encephalopathy, Bilirubin (en, replaced) Encephalopathy, Hyperbilirubinemic (en, replaced) Bilirubin Encephalopathy (en, replaced) Encephalopathia e bilirubino (la-FI, replaced) Icterus nuclearis (la-FI, replaced) Kernicterus (en-FI, replaced) |
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