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Keratins
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Keratins 7 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ Keratins 7 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ Keratins 7 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ Keratins 7 coordinate concepts4 subordinate conceptsX |
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historyNote*: | 2007(1966)
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publicMeSHNote*: | 2007; see KERATIN 1966-2006; KERATIN-ASSOCIATED PROTEINS was indexed under KERATIN 2000-2006, & under PROTEINS 1993-1999
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Scope note: | A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
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activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Keratiinit (fi) XSarveisaine (fi, replaced) Keratiini (fi, replaced) Glycosylated Keratin (en, replaced) Keratin (en, replaced) Cytokeratin (en, replaced) Ceratinum (la-FI, replaced) Keratinum (la-FI, replaced) |
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