ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycosides ∟ Glucosides ∟ Etoposide 7 coordinate concepts ∟ Amygdalin \| ∟ Arbutin \| ∟ Chloralose \| ∟ Esculin \| ∟ Methylglucosides \| ∟ Teniposide \| ∟ Thioglucosides Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Hydrocarbons ∟ Hydrocarbons, Cyclic ∟ Hydrocarbons, Aromatic ∟ Benzene Derivatives ∟ Benzyl Compounds ∟ Lignans ∟ Podophyllotoxin ∟ Etoposide 7 coordinate concepts ∟ Amygdalin \| ∟ Arbutin \| ∟ Chloralose \| ∟ Esculin \| ∟ Methylglucosides \| ∟ Teniposide \| ∟ Thioglucosides Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Hydrocarbons ∟ Hydrocarbons, Cyclic ∟ Hydrocarbons, Aromatic ∟ Polycyclic Hydrocarbons, Aromatic ∟ Naphthalenes ∟ Tetrahydronaphthalenes ∟ Podophyllotoxin ∟ Etoposide 7 coordinate concepts ∟ Amygdalin \| ∟ Arbutin \| ∟ Chloralose \| ∟ Esculin \| ∟ Methylglucosides \| ∟ Teniposide \| ∟ Thioglucosides Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Polycyclic Hydrocarbons, Aromatic ∟ Naphthalenes ∟ Tetrahydronaphthalenes ∟ Podophyllotoxin ∟ Etoposide 7 coordinate concepts ∟ Amygdalin \| ∟ Arbutin \| ∟ Chloralose \| ∟ Esculin \| ∟ Methylglucosides \| ∟ Teniposide \| ∟ Thioglucosides X
Broader terms:	Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycosides ∟ Glucosides ∟ Etoposide Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Hydrocarbons ∟ Hydrocarbons, Cyclic ∟ Hydrocarbons, Aromatic ∟ Benzene Derivatives ∟ Benzyl Compounds ∟ Lignans ∟ Podophyllotoxin ∟ Etoposide Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Hydrocarbons ∟ Hydrocarbons, Cyclic ∟ Hydrocarbons, Aromatic ∟ Polycyclic Hydrocarbons, Aromatic ∟ Naphthalenes ∟ Tetrahydronaphthalenes ∟ Podophyllotoxin ∟ Etoposide Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Polycyclic Hydrocarbons, Aromatic ∟ Naphthalenes ∟ Tetrahydronaphthalenes ∟ Podophyllotoxin ∟ Etoposide Glucosides > Glycosides > Carbohydrates > Medical Subject Headings (MeSH) Podophyllotoxin > Lignans > Benzyl Compounds > Benzene Derivatives > Hydrocarbons, Aromatic > Hydrocarbons, Cyclic > Hydrocarbons > Organic Chemicals > Medical Subject Headings (MeSH) Podophyllotoxin > Tetrahydronaphthalenes > Naphthalenes > Polycyclic Hydrocarbons, Aromatic > Hydrocarbons, Aromatic > Hydrocarbons, Cyclic > Hydrocarbons > Organic Chemicals > Medical Subject Headings (MeSH) Podophyllotoxin > Tetrahydronaphthalenes > Naphthalenes > Polycyclic Hydrocarbons, Aromatic > Polycyclic Compounds > Medical Subject Headings (MeSH) X
History note:	Glucosides (1975) \| Glycosides (1973-1974) \| Podophyllotoxin (1973-1974)/analogs & derivatives (1975)X
historyNote*:	87(81); was see under PODOPHYLLOTOXIN 1981-86; was VP 16-213 see under PODOPHYLLOTOXIN 1976-80 X
onlineNote*:	use ETOPOSIDE to search VP 16-213 1976-80 X
publicMeSHNote*:	87; was see under PODOPHYLLOTOXIN 1981-86; was VP 16-213 see under PODOPHYLLOTOXIN 1976-80 X
Scope note:	A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. X
activeMeSHYear*:	2007X
dateCreated*:	1975-07-25X
dateEstablished*:	1987-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	SHX
Type:	Concept X
Coordinate terms:	Amygdalin \| Arbutin \| Chloralose \| Esculin \| Methylglucosides \| Teniposide \| Thioglucosides X
URI:	X
Labels and equivalent concepts:	Etoposidi (fi) Etoposid (sv) Vepesid (sv, replaced) Pierre Fabre Brand of Etoposide (en, replaced) Prasfarma Brand of Etoposide (en, replaced) Pharmacia Brand of Etoposide (en, replaced) Pharmachemie Brand of Etoposide (en, replaced) Onkoworks Brand of Etoposide (en, replaced) ribosepharm Brand of Etoposide (en, replaced) Sanfer Brand of Etoposide (en, replaced) Teva Brand of Etoposide (en, replaced) Tedec Meiji Brand of Etoposide (en, replaced) Novartis Brand of Etoposide (en, replaced) Medac Brand of Etoposide (en, replaced) Demethyl Epipodophyllotoxin Ethylidine Glucoside (en, replaced) Bristol-Myers Squibb Brand of Etoposide (en, replaced) Bristol-Myers Brand of Etoposide (en, replaced) Baxter Oncology Brand of Etoposide (en, replaced) Eposide (en, replaced) Eto CS (en, replaced) Lemery Brand of Etoposide (en, replaced) Gry Brand of Etoposide (en, replaced) Ferrer Brand of Etoposide (en, replaced) Etomedac (en, replaced) Baxter Brand of Etoposide (en, replaced) Etoposidum (la-FI, replaced) X
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