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Myelin Basic Proteins
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Myelin Basic Proteins 3 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ Myelin Basic Proteins 3 coordinate concepts1 subordinate conceptX |
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Annotation: | /biosyn /drug eff /physiol /ultrastruct permitted; note X ref: do not index under ENCEPHALOMYELITIS, ALLERGIC unless the disease is discussed; DF: ENCEPH BASIC PROTEINS
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History note: | Nerve Tissue Proteins (1966-1972)X |
historyNote*: | 96; was ENCEPHALITOGENIC BASIC PROTEINS 1973-95 (Prov 1974); MYELIN BASIC PROTEINS was see ENCEPHALITOGENIC BASIC PROTEINS 1979-95
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publicMeSHNote*: | 96; was ENCEPHALITOGENIC BASIC PROTEINS 1974-95; MYELIN BASIC PROTEINS was see ENCEPHALITOGENIC BASIC PROTEINS 1979-95
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Scope note: | A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (MBP) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (ENCEPHALOMYELITIS, ALLERGIC). In the peripheral nervous system, myelin basic protein 18.5-kDa is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, 133)
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activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1974-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | SYSTEMX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Myeliinin emäksiset proteiinit (fi) XEnkefalitogeeniset proteiinit (fi, replaced) MBP (fi, replaced) Myeliinin emäksinen proteiini (fi, replaced) Enkefalitogeeninen proteiini (fi, replaced) Proteins, Encephalitogenic Basic (en, replaced) Encephalitogenic Basic Protein (en, replaced) Encephalitogenic Basic Proteins (en, replaced) Protein, Encephalitogenic Basic (en, replaced) Basic Proteins, Encephalitogenic (en, replaced) |
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