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Diphtheria Toxin
Hierarchy: | ∟ ∟ ∟ ∟ Diphtheria Toxin 13 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Diphtheria Toxin 13 coordinate conceptsX |
Broader terms: | |
Annotation: | /antag permitted but consider also DIPHTHERIA ANTITOXIN
X |
Scope note: | An ADP-ribosylating EXOTOXIN produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono ADPribose transferase which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
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activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2005-07-20X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | NLMX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Kurkkumätätoksiini (fi) XDifteriatoksiini (fi, replaced) Corynebacterium diphteriae -toksiini (fi, replaced) Difteritoxin (sv) Toxin, Corynebacterium Diphtheriae (en, replaced) Corynebacterium Diphtheriae Toxin (en, replaced) |
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