ONKI3 | Medical Subject Headings

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Cholesterol 7-alpha-Hydroxylase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase 10 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase 10 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase 10 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase 10 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Cholesterol 7-alpha-Hydroxylase Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Hemeproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
History note:	Cholesterol (1974) \| Steroid Hydroxylases (1974)X
historyNote*:	2003 (1975) X
publicMeSHNote*:	2003; see CHOLESTEROL 7 ALPHA-MONOOXYGENASE 1997-2002, see CHOLESTEROL-7-HYDROXYLASE 1991-1996, see STEROID HYDROXYLASES 1975-1990 X
Scope note:	A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS. X
activeMeSHYear*:	2007X
dateCreated*:	1974-11-19X
dateEstablished*:	1991-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	agsX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| Aldosterone Synthase \| Aromatase \| Cholesterol Side-Chain Cleavage Enzyme \| Cytochrome P-450 CYP27A1 \| Steroid 11-beta-Hydroxylase \| Steroid 12-alpha-Hydroxylase \| Steroid 16-alpha-Hydroxylase \| Steroid 17-alpha-Hydroxylase \| Steroid 21-Hydroxylase X
URI:	X
Labels and equivalent concepts:	Kolesteroli-7-alfa-hydroksylaasi (fi) Kolesterol-7-alfa-monooxygenas (sv) CYP7A (en, replaced) Cytochrome P-450 CYP7 (en, replaced) Cytochrome P450 7 (en, replaced) CYP7 (en, replaced) CYP 7A (en, replaced) Cholesterol 7alpha-Hydroxylase (en, replaced) Cholesterol-7-Hydroxylase (en, replaced) CYP 7 (en, replaced) Cholesterol 7-alpha-Monooxygenase (en, replaced) X
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