ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Cholesterol Side-Chain Cleavage Enzyme

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Multienzyme Complexes ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase Medical Subject Headings (MeSH) ∟ Macromolecular Substances ∟ Multiprotein Complexes ∟ Multienzyme Complexes ∟ Cholesterol Side-Chain Cleavage Enzyme 33 coordinate concepts ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase \| ∟ Steroid 21-Hydroxylase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ Anthranilate Synthase \| ∟ Aspartate Carbamoyltransferase \| ∟ Aspartokinase Homoserine Dehydrogenase \| ∟ Cytochrome b6f Complex \| ∟ Electron Transport Chain Complex Proteins \| ∟ Electron Transport Complex I \| ∟ Electron Transport Complex IV \| ∟ Fatty Acid Synthetase Complex \| ∟ Glycine Decarboxylase Complex \| ∟ Ketoglutarate Dehydrogenase Complex \| ∟ Lactose Synthase \| ∟ Phosphoenolpyruvate Sugar Phosphotransferase System \| ∟ Photosynthetic Reaction Center Complex Proteins \| ∟ Photosystem I Protein Complex \| ∟ Photosystem II Protein Complex \| ∟ Polyketide Synthases \| ∟ Prostaglandin-Endoperoxide Synthases \| ∟ Proteasome Endopeptidase Complex \| ∟ Pyruvate Dehydrogenase Complex \| ∟ Succinate Cytochrome c Oxidoreductase \| ∟ Sucrase-Isomaltase Complex \| ∟ Tryptophan Synthase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Multienzyme Complexes ∟ Cholesterol Side-Chain Cleavage Enzyme Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Cholesterol Side-Chain Cleavage Enzyme Medical Subject Headings (MeSH) ∟ Macromolecular Substances ∟ Multiprotein Complexes ∟ Multienzyme Complexes ∟ Cholesterol Side-Chain Cleavage Enzyme Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Hemeproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Multienzyme Complexes > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Multienzyme Complexes > Multiprotein Complexes > Macromolecular Substances > Medical Subject Headings (MeSH) X
History note:	Cholesterol (1971-1974) \| Multienzyme Complexes (1973-1974) \| Oxidoreductases (1971-1974)X
historyNote*:	2003 (1975) X
publicMeSHNote*:	2003; see CHOLESTEROL MONOOXYGENASE 1997-2002, see CHOLESTEROL DESMOLASE 1988-1996, see OXIDOREDUCTASES 1975-1987 X
Scope note:	A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones. X
activeMeSHYear*:	2005 \| 2006 \| 2006A \| 2007X
dateCreated*:	1974-11-19X
dateEstablished*:	1988-01-01X
dateRevised*:	2005-07-11X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| Aldosterone Synthase \| Aromatase \| Cholesterol 7-alpha-Hydroxylase \| Cytochrome P-450 CYP27A1 \| Steroid 11-beta-Hydroxylase \| Steroid 12-alpha-Hydroxylase \| Steroid 16-alpha-Hydroxylase \| Steroid 17-alpha-Hydroxylase \| Steroid 21-Hydroxylase \| Anthranilate Phosphoribosyltransferase \| Anthranilate Synthase \| Aspartate Carbamoyltransferase \| Aspartokinase Homoserine Dehydrogenase \| Cytochrome b6f Complex \| Electron Transport Chain Complex Proteins \| Electron Transport Complex I \| Electron Transport Complex IV \| Fatty Acid Synthetase Complex \| Glycine Decarboxylase Complex \| Ketoglutarate Dehydrogenase Complex \| Lactose Synthase \| Phosphoenolpyruvate Sugar Phosphotransferase System \| Photosynthetic Reaction Center Complex Proteins \| Photosystem I Protein Complex \| Photosystem II Protein Complex \| Polyketide Synthases \| Prostaglandin-Endoperoxide Synthases \| Proteasome Endopeptidase Complex \| Pyruvate Dehydrogenase Complex \| Succinate Cytochrome c Oxidoreductase \| Sucrase-Isomaltase Complex \| Tryptophan Synthase X
URI:	X
Labels and equivalent concepts:	Kolesterolin sivuketjuja pilkkova enstsyymi (fi) Kolesterolmonooxygenas (som spaltar sidokedja) (sv) Cytochrome P-450(scc) (en, replaced) Cytochrome P450 11A1 (en, replaced) Cytochrome P450scc (en, replaced) Cytochrome P-450 CYP11A1 (en, replaced) CYP11A1 (en, replaced) Cholesterol Desmolase (en, replaced) Cholesterol Monooxygenase (Side-Chain-Cleaving) (en, replaced) CYP 11A1 (en, replaced) 20,22-Desmolase (en, replaced) X
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