ONKI3 | Medical Subject Headings

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The ONKI Team

Jouni Tuominen, Living Lab contact person, APIs, widgets, publishing of ontologies, etc.
Eero Hyvönen, professor, head of research group

Former members: Kim Viljanen, Rami Alatalo.

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suomeksi på svenska in English

The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Biotransformation

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Biochemical Phenomena, Metabolism, and Nutrition ∟ Metabolism ∟ Pharmacokinetics ∟ Biotransformation 4 coordinate concepts 2 subordinate concepts ∟ Metabolic Clearance Rate \| ∟ Metabolic Detoxication, Drug ∟ Area Under Curve \| ∟ Biological Availability \| ∟ Therapeutic Equivalency \| ∟ Tissue Distribution Medical Subject Headings (MeSH) ∟ Chemical and Pharmacologic Phenomena ∟ Biopharmaceutics ∟ Pharmacokinetics ∟ Biotransformation 4 coordinate concepts 2 subordinate concepts ∟ Metabolic Clearance Rate \| ∟ Metabolic Detoxication, Drug ∟ Area Under Curve \| ∟ Biological Availability \| ∟ Therapeutic Equivalency \| ∟ Tissue Distribution X
Broader terms:	Medical Subject Headings (MeSH) ∟ Biochemical Phenomena, Metabolism, and Nutrition ∟ Metabolism ∟ Pharmacokinetics ∟ Biotransformation Medical Subject Headings (MeSH) ∟ Chemical and Pharmacologic Phenomena ∟ Biopharmaceutics ∟ Pharmacokinetics ∟ Biotransformation Pharmacokinetics > Metabolism > Biochemical Phenomena, Metabolism, and Nutrition > Medical Subject Headings (MeSH) Pharmacokinetics > Biopharmaceutics > Chemical and Pharmacologic Phenomena > Medical Subject Headings (MeSH) X
Narrower terms:	Metabolic Clearance Rate \| Metabolic Detoxication, Drug X
Annotation:	restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM); or /metab (for microorganisms); do not confuse with BIODEGRADATION: reduction of "pollutant chemicals, organic wastes, pesticides & implantable materials" X
historyNote*:	70(66) X
publicMeSHNote*:	70 X
Scope note:	The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1999-01-01X
dateEstablished*:	1970-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	Area Under Curve \| Biological Availability \| Therapeutic Equivalency \| Tissue Distribution X
URI:	X
Labels and equivalent concepts:	Biotransformaatio (fi) Biotransformering (sv) Metabolisk aktivering (sv, replaced) Metabolic Activation (en, replaced) Biotransformatio (la-FI, replaced) X
Share:	X