ONKI3 | Medical Subject Headings

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The way concept relations are shown: separately in hierarchy

Histocompatibility Antigens Class II

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Antigens, Surface ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class II 3 coordinate concepts 1 subordinate concept ∟ HLA-D Antigens ∟ Histocompatibility Antigens Class I \| ∟ HLA Antigens \| ∟ Minor Histocompatibility Antigens Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Isoantigens ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class II 3 coordinate concepts 1 subordinate concept ∟ HLA-D Antigens ∟ Histocompatibility Antigens Class I \| ∟ HLA Antigens \| ∟ Minor Histocompatibility Antigens X
Broader terms:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Antigens, Surface ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class II Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Isoantigens ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class II Histocompatibility Antigens > Antigens, Surface > Antigens > Biological Factors > Medical Subject Headings (MeSH) Histocompatibility Antigens > Isoantigens > Antigens > Biological Factors > Medical Subject Headings (MeSH) X
Narrower terms:	HLA-D Antigens X
Annotation:	human & animal; GEN: prefer specifics; see also HLA ANTIGENS & specifics for human; X ref IA ANTIGENS refers to any class II histocompatibility antigen X
History note:	Histocompatibility Antigens (1973-1980) \| HLA Antigens (1975-1980) \| Isoantigens (1973-1980)X
historyNote*:	89; was ANTIGENS, IMMUNE RESPONSE 1981-88; I-A-ANTIGEN was NM 1987-93 X
onlineNote*:	use HISTOCOMPATIBILITY ANTIGENS CLASS II to search ANTIGENS, IMMUNE RESPONSE 1981-88 & I-A-ANTIGEN 1987-93 X
publicMeSHNote*:	89; was ANTIGENS, IMMUNE RESPONSE 1981-88; I-A-ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS II 1987-93 X
Scope note:	Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1980-05-13X
dateEstablished*:	1981-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	SHX
Type:	Concept X
Coordinate terms:	Histocompatibility Antigens Class I \| HLA Antigens \| Minor Histocompatibility Antigens X
URI:	X
Labels and equivalent concepts:	Kudossopeutuvuusantigeenit luokka II (fi) Histokompatibiliteettiantigeeni luokka II (fi, replaced) Kudossopeutuvuusantigeeni luokka II (fi, replaced) Histokompatibiliteettiantigeenit luokka II (fi, replaced) Histokompatibilitetsantigener klass II (sv) Immune Response Antigens (en, replaced) Ia-Like Antigens (en, replaced) Immune-Response-Associated Antigens (en, replaced) Ia Antigens (en, replaced) IA Antigen (en, replaced) Class II Antigens (en, replaced) Class II Antigen (en, replaced) Class II Histocompatibility Antigens (en, replaced) Class II Major Histocompatibility Antigens (en, replaced) I-A-Antigen (en, replaced) I-A Antigen (en, replaced) Antigens, Immune Response (en, replaced) X
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