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The way concept relations are shown:
Anti-Inflammatory Agents, Non-Steroidal
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal 1 coordinate concept1 subordinate conceptX |
Broader terms: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal ∟ ∟ ∟ ∟ ∟ ∟ ∟ Anti-Inflammatory Agents, Non-Steroidal |
Narrower terms: | |
Annotation: | GEN or unspecified: prefer specifics; DF: NSAID
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History note: | |
historyNote*: | 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89
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onlineNote*: | use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89
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publicMeSHNote*: | 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89
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Scope note: | Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
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activeMeSHYear*: | |
dateCreated*: | 1986-06-23X |
dateEstablished*: | 1987-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | SHX |
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Labels and equivalent concepts: | NSAID (fi) XEi-steroidaalinen anti-inflammatorinen lääke (fi, replaced) Ei-steroidaaliset anti-inflammatoriset lääkkeet (fi, replaced) Antiinflammatoriska medel, icke-steroida (sv) NSAID (sv, replaced) NSAIDs (en, replaced) Nonsteroidal Anti-Inflammatory Agents (en, replaced) Non-Steroidal Anti-Inflammatory Agents (en, replaced) Antiinflammatory Agents, Non Steroidal (en, replaced) Antiinflammatory Agents, Nonsteroidal (en, replaced) Antirheumatic Agents, Non-Steroidal (en, replaced) Anti Inflammatory Agents, Nonsteroidal (en, replaced) |
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