ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Amyotrophic Lateral Sclerosis

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Spinal Cord Diseases ∟ Amyotrophic Lateral Sclerosis 14 coordinate concepts ∟ Bulbar Palsy, Progressive \| ∟ Muscular Atrophy, Spinal \| ∟ Poliomyelitis \| ∟ Epidural Abscess \| ∟ Myelitis \| ∟ Spinal Cord Compression \| ∟ Spinal Cord Injuries \| ∟ Spinal Cord Neoplasms \| ∟ Spinal Cord Vascular Diseases \| ∟ Spinocerebellar Degenerations \| ∟ Stiff-Person Syndrome \| ∟ Subacute Combined Degeneration \| ∟ Syringomyelia \| ∟ Tabes Dorsalis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Motor Neuron Disease ∟ Amyotrophic Lateral Sclerosis 14 coordinate concepts ∟ Bulbar Palsy, Progressive \| ∟ Muscular Atrophy, Spinal \| ∟ Poliomyelitis \| ∟ Epidural Abscess \| ∟ Myelitis \| ∟ Spinal Cord Compression \| ∟ Spinal Cord Injuries \| ∟ Spinal Cord Neoplasms \| ∟ Spinal Cord Vascular Diseases \| ∟ Spinocerebellar Degenerations \| ∟ Stiff-Person Syndrome \| ∟ Subacute Combined Degeneration \| ∟ Syringomyelia \| ∟ Tabes Dorsalis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neuromuscular Diseases ∟ Motor Neuron Disease ∟ Amyotrophic Lateral Sclerosis 14 coordinate concepts ∟ Bulbar Palsy, Progressive \| ∟ Muscular Atrophy, Spinal \| ∟ Poliomyelitis \| ∟ Epidural Abscess \| ∟ Myelitis \| ∟ Spinal Cord Compression \| ∟ Spinal Cord Injuries \| ∟ Spinal Cord Neoplasms \| ∟ Spinal Cord Vascular Diseases \| ∟ Spinocerebellar Degenerations \| ∟ Stiff-Person Syndrome \| ∟ Subacute Combined Degeneration \| ∟ Syringomyelia \| ∟ Tabes Dorsalis X
Broader terms:	Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Spinal Cord Diseases ∟ Amyotrophic Lateral Sclerosis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Motor Neuron Disease ∟ Amyotrophic Lateral Sclerosis Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neuromuscular Diseases ∟ Motor Neuron Disease ∟ Amyotrophic Lateral Sclerosis Spinal Cord Diseases > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Motor Neuron Disease > Neurodegenerative Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Motor Neuron Disease > Neuromuscular Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) X
Scope note:	A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) X
activeMeSHYear*:	2003 \| 2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1999-01-01X
dateRevised*:	2002-07-02X
recordAuthorizer*:	sjnX
recordMaintainer*:	mdbX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	Bulbar Palsy, Progressive \| Muscular Atrophy, Spinal \| Poliomyelitis \| Epidural Abscess \| Myelitis \| Spinal Cord Compression \| Spinal Cord Injuries \| Spinal Cord Neoplasms \| Spinal Cord Vascular Diseases \| Spinocerebellar Degenerations \| Stiff-Person Syndrome \| Subacute Combined Degeneration \| Syringomyelia \| Tabes Dorsalis X
URI:	X
Labels and equivalent concepts:	Amyotrofinen lateraaliskleroosi (fi) ALS (fi, replaced) Liikeratakovettumatauti (fi, replaced) Amyotrofisk lateralskleros (sv) ALS (sv, replaced) Motor Neuron Disease, Amyotrophic Lateral Sclerosis (en, replaced) Lou Gehrig's Disease (en, replaced) Dementia With Amyotrophic Lateral Sclerosis (en, replaced) Gehrig's Disease (en, replaced) Guam Form of Amyotrophic Lateral Sclerosis (en, replaced) Lou Gehrig Disease (en, replaced) ALS (Amyotrophic Lateral Sclerosis) (en, replaced) Sclerosis lateralis amyotrophica (la-FI, replaced) X
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