ONKI3 | Medical Subject Headings

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5-Aminolevulinate Synthetase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Acyltransferases ∟ 5-Aminolevulinate Synthetase 23 coordinate concepts ∟ 1-Acylglycerol-3-Phosphate O-Acyltransferase \| ∟ 1-Acylglycerophosphocholine O-Acyltransferase \| ∟ 2-Isopropylmalate Synthase \| ∟ 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase \| ∟ Acetyl-CoA C-Acyltransferase \| ∟ Acetyltransferases \| ∟ Acyl-Carrier Protein S-Malonyltransferase \| ∟ Aminoacyltransferases \| ∟ Arylalkylamine N-Acetyltransferase \| ∟ Arylamine N-Acetyltransferase \| ∟ ATP Citrate (pro-S)-Lyase \| ∟ Carnitine Acyltransferases \| ∟ Citrate (si)-Synthase \| ∟ Diacylglycerol O-Acyltransferase \| ∟ Glycerol-3-Phosphate O-Acyltransferase \| ∟ Homoserine O-Succinyltransferase \| ∟ Hydroxymethylglutaryl-CoA Synthase \| ∟ Malate Synthase \| ∟ Phosphatidylcholine-Sterol O-Acyltransferase \| ∟ Retinol O-Fatty-Acyltransferase \| ∟ Serine C-Palmitoyltransferase \| ∟ Sphingosine N-Acyltransferase \| ∟ Sterol O-Acyltransferase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Acyltransferases ∟ 5-Aminolevulinate Synthetase Acyltransferases > Transferases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
History note:	Acyltransferases (1966-1971)X
historyNote*:	98(72) X
publicMeSHNote*:	98; see AMINOLEVULINIC ACID SYNTHETASE 1972-97 X
Scope note:	An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2006A \| 2006B \| 2007X
dateCreated*:	1999-01-01X
dateEstablished*:	1973-01-01X
dateRevised*:	2005-07-29X
recordAuthorizer*:	jlsX
recordMaintainer*:	jlsX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	1-Acylglycerol-3-Phosphate O-Acyltransferase \| 1-Acylglycerophosphocholine O-Acyltransferase \| 2-Isopropylmalate Synthase \| 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase \| Acetyl-CoA C-Acyltransferase \| Acetyltransferases \| Acyl-Carrier Protein S-Malonyltransferase \| Aminoacyltransferases \| Arylalkylamine N-Acetyltransferase \| Arylamine N-Acetyltransferase \| ATP Citrate (pro-S)-Lyase \| Carnitine Acyltransferases \| Citrate (si)-Synthase \| Diacylglycerol O-Acyltransferase \| Glycerol-3-Phosphate O-Acyltransferase \| Homoserine O-Succinyltransferase \| Hydroxymethylglutaryl-CoA Synthase \| Malate Synthase \| Phosphatidylcholine-Sterol O-Acyltransferase \| Retinol O-Fatty-Acyltransferase \| Serine C-Palmitoyltransferase \| Sphingosine N-Acyltransferase \| Sterol O-Acyltransferase X
URI:	X
Labels and equivalent concepts:	5-aminolevulinaattisyntetaasi (fi) 5-aminolevulinatsyntetas (sv) delta-Aminolevulinic Acid Synthetase (en, replaced) delta-Aminolevulinate Synthase (en, replaced) Aminolevulinic Acid Synthetase (en, replaced) X
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