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Presenilins
Hierarchy: | ∟ ∟ ∟ ∟ Presenilins 25 coordinate concepts2 subordinate conceptsX |
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History note: | |
historyNote*: | 2007
X |
publicMeSHNote*: | 2007
X |
Scope note: | Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PROTEIN precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 2006-07-05X |
dateEstablished*: | 2007-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | lktX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Preseniliinit (fi) XPresenilin (en, replaced) |
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