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Complement Membrane Attack Complex
Hierarchy: | |
Broader terms: | |
Annotation: | DF: COMPLEMENT MAC
X |
History note: | Complement (1973-1989)X |
historyNote*: | 90
X |
publicMeSHNote*: | 90
X |
Scope note: | A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC.
X |
activeMeSHYear*: | |
dateCreated*: | 1989-05-25X |
dateEstablished*: | 1990-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | AGSX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Komplementin membraania tuhoava kompleksi (fi) XMembranattackkomplex (sv) Membrane Attack Complex (en, replaced) Terminal Complement Complex (en, replaced) Cytolytic Terminal Complement Complex (en, replaced) Complement Complex C5b-9 (en, replaced) C5b-8-poly-C9 (en, replaced) C5b-9 (en, replaced) C 5b-9 (en, replaced) |
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