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The way concept relations are shown:
Pregnancy-Associated Plasma Protein-A
Hierarchy: | ∟ ∟ ∟ ∟ Pregnancy-Associated Plasma Protein-A 16 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Pregnancy-Associated Plasma Protein-A 16 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Pregnancy-Associated Plasma Protein-A 16 coordinate conceptsX |
Broader terms: | |
History note: | Alpha Globulins (1966-1979) | Alpha Macroglobulins (1976-1979) | Blood Proteins (1966-1979) | Glycoproteins (1966-1979) | Pregnancy (1966-1979)X |
historyNote*: | 2004 (1996)
X |
publicMeSHNote*: | 2004; for PREGNANCY-ASSOCIATED ALPHA-PLASMA PROTEIN see PREGNANCY-ASSOCIATED ALPHA-PLASMA PROTEIN 1991-2003, see PREGNANCY PROTEINS 1980-1990
X |
Scope note: | A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.
X |
activeMeSHYear*: | |
dateCreated*: | 1979-02-22X |
dateEstablished*: | 1991-01-01X |
dateRevised*: | 2004-07-13X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | sjnX |
recordOriginator*: | RLSX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Raskauteen liittyvä plasman proteiini A (fi) XPAPP-alpha (en, replaced) Pregnancy Associated alpha Plasma Protein (en, replaced) Pregnancy-Associated alpha-Plasma Protein (en, replaced) PAPP-A (en, replaced) Insulin-Like-Growth Factor Binding Protein-4 Protease (en, replaced) IGFBP-4 Protease (en, replaced) IGFBP-4-Specific Proteinase (en, replaced) Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease (en, replaced) IGFBP-4 Metalloproteinase (en, replaced) |
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