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Complement C9
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historyNote*: | 2006 (1975)
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publicMeSHNote*: | 2006; see COMPLEMENT 9 1978-2005, see COMPLEMENT 1975-1977
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Scope note: | A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
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activeMeSHYear*: | |
dateCreated*: | 1974-11-11X |
dateEstablished*: | 1978-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Komplementti C9 (fi) XC9 (fi, replaced) Komplement 9 (sv) Complement Component 9 (en, replaced) Complement 9 (en, replaced) C9 Complement (en, replaced) |
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