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beta 2-Microglobulin
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ beta 2-Microglobulin 7 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ beta 2-Microglobulin 7 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
Annotation: | /biosyn /physiol /blood permitted
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History note: | Beta Globulins (1973-1974)X |
historyNote*: | 91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83
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onlineNote*: | use BETA 2-MICROGLOBULIN tosearch BETA 2 MICROGLOBULIN 1984-90
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publicMeSHNote*: | 91; was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83
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Scope note: | An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
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activeMeSHYear*: | |
dateCreated*: | 1974-11-19X |
dateEstablished*: | 1984-01-01X |
dateRevised*: | 2004-07-07X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | NLMX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Beeta2-mikroglobuliini (fi) XBeeta-2-mikroglobuliini (fi, replaced) beta 2-mikroglobulin (sv) Thymotaxin (en, replaced) |
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