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The way concept relations are shown:
Cytochrome P-450 CYP3A
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Cytochrome P-450 CYP3A 14 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Cytochrome P-450 CYP3A 14 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Cytochrome P-450 CYP3A 14 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Cytochrome P-450 CYP3A 14 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
historyNote*: | 2006(1980)
X |
publicMeSHNote*: | 2006; CYTOCHROME P-450 CYP3A was indexed under ARYL HYDROCARBON HYDROXYLASES & OXIDOREDUCTASES, N-DEMETHYLATING 1980-2005
X |
Scope note: | A cytochrome P-450 monooxygenase that is involved in an NADPH-dependent electron transport pathway by oxidizing a variety of structurally unrelated compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN.
X |
activeMeSHYear*: | |
dateCreated*: | 2005-06-30X |
dateEstablished*: | 2006-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | AKEX |
recordOriginator*: | AKEX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Sytokromi P-450 CYP3A (fi) XErythromycin N-Demethylase (en, replaced) Cytochrome P450 3A (en, replaced) Cytochrome P-450IIIA (en, replaced) CYP3A (en, replaced) Citocromo P-450 CYP3A (es) Cytochrom P-450 CYP3A (de) cytochrom P-450 CYP3A (cs) CYP3A (es, replaced) CYP3A (cs, replaced) |
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