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GRB2 Adaptor Protein
Hierarchy: | ∟ ∟ ∟ ∟ ∟ GRB2 Adaptor Protein 23 coordinate concepts∟ ∟ ∟ ∟ ∟ GRB2 Adaptor Protein 23 coordinate concepts∟ ∟ ∟ ∟ ∟ GRB2 Adaptor Protein 23 coordinate conceptsX |
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historyNote*: | 2006(1992)
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publicMeSHNote*: | 2006; GROWTH FACTOR RECEPTOR-BOUND PROTEIN-2 was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2005, & under PROTEINS 1992-2004
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Scope note: | A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).
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activeMeSHYear*: | |
dateCreated*: | 2005-06-30X |
dateEstablished*: | 2006-01-01X |
dateRevised*: | 2005-07-13X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | DRCX |
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Labels and equivalent concepts: | GRB2-adaptoriproteiini (fi) XGrowth Factor Receptor-Bound Protein-2 (en, replaced) Grb3-3 Adaptor Protein (en, replaced) Abundant Src Homology Protein (en, replaced) Proteína Adaptadora GRB2 (es) GRB2-Adaptorprotein (de) adaptorový protein GRB2 (cs) Proteína 2 de Unión al Receptor de Factores de Crecimiento (es, replaced) GRB2-Adaptorprotein, Grb3-3-Isoform (de, replaced) adaptorový protein GRB2 - isoforma Grb3-3 (cs, replaced) |
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