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Complement C1 Inhibitor Protein
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Complement C1 Inhibitor Protein 1 subordinate concept∟ ∟ ∟ ∟ ∟ Complement C1 Inhibitor Protein 1 subordinate conceptX |
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Annotation: | do not confuse with COMPLEMENT C1 INACTIVATOR PROTEINS
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History note: | Complement C1 Inactivator Proteins (1970-2005)X |
historyNote*: | 2006
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publicMeSHNote*: | 2006
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Scope note: | An endogenous serine protease inhibitor (SERPINS). It is a 105-kDA plasma glycoprotein, encoded by C1NH gene and produced primarily by the liver and monocytes. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from hereditary ANGIONEUROTIC EDEMA.
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activeMeSHYear*: | |
dateCreated*: | 2005-06-30X |
dateEstablished*: | 2006-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | lktX |
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Labels and equivalent concepts: | C1-INH (fi) XComplement C1-Inhibitor Protein (en, replaced) Plasma Protease C1 Inhibitor (en, replaced) C1-Inhibitor Protein (en, replaced) C1-INH Protein (en, replaced) Proteína Inhibidora del Complemento C1 (es) Komplement-C1-Inhibitorprotein (de) komplement C1 - inhibiční protein (cs) inhibiční protein komplementu C1 (cs, replaced) komplement C1 - inhibitor (cs, replaced) C1-INH protein (cs, replaced) |
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