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Transient Receptor Potential Channels
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Transient Receptor Potential Channels 5 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Transient Receptor Potential Channels 5 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Transient Receptor Potential Channels 5 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Transient Receptor Potential Channels 5 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Transient Receptor Potential Channels 5 coordinate concepts4 subordinate conceptsX |
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Annotation: | note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN
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History note: | |
historyNote*: | 2006
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publicMeSHNote*: | 2006
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Scope note: | A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN repeats are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or PHOSPHOLIPASE C.
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activeMeSHYear*: | |
dateCreated*: | 2005-06-30X |
dateEstablished*: | 2006-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | ssbX |
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Labels and equivalent concepts: | TRPC (fi) XTRP Membrane Proteins (en, replaced) TRP Cation Channels (en, replaced) Canales TRP (es) Transiente Rezeptor-Potential-Kanäle (de) kationtové kanály TRP (cs) Canales Receptores Transitorios de Potencial (es, replaced) Proteínas TRP de la Membrana (es, replaced) Canales Catiónicos TRP (es, replaced) TRP kanály (cs, replaced) kanály přechodných receptorových potenciálů (cs, replaced) |
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