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The way concept relations are shown:
Integrin alpha6beta4
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alpha6beta4 7 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alpha6beta4 7 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ |
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History note: | |
historyNote*: | 2003; use INTEGRIN ALPHA6BETA4 (NM) 1988-2002
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publicMeSHNote*: | 2003; INTEGRIN ALPHA6BETA4 was indexed under INTEGRINS; & ANTIGENS, SURFACE 1988-2002
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Scope note: | This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
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activeMeSHYear*: | |
dateCreated*: | 2002-07-02X |
dateEstablished*: | 2003-01-01X |
dateRevised*: | 2005-07-18X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | MDJX |
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Labels and equivalent concepts: | Alfa6beeta4-integriini (fi) XLaminin-5 Receptor (alpha6beta4 Integrin) (en, replaced) TSP-180 (en, replaced) Tumor Specific Protein-180 Complex (en, replaced) Integrin alpha(6),beta(4) (en, replaced) alpha6 beta4 Integrin (en, replaced) alpha(6)beta(4) Epithelial Integrin (en, replaced) alpha(6)beta(4) Integrin (en, replaced) A9 Antigen (en, replaced) Integrina alfa6beta4 (es) Integrin Alpha6-Beta4 (de) integrin alfa6beta4 (cs) |
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